Senior Consultant, Orthopaedics, Artemis Hospitals, Gurugram
Part 7 of 12 in Newer Advances in Arthroscopic Surgeries of Knee and Shoulder
Cartilage Repair: Microfracture, OATS and Autologous Chondrocyte Implantation
August 30, 2026
Every arthroscopic surgery is ultimately aimed at protecting cartilage over the long term, and cartilage treatment itself has evolved from simple repair toward regeneration and tissue engineering. The right technique depends heavily on the size of the defect.
Microfracture and OATS
For small defects up to 4 to 6 mm, microfracture creates small holes through the subchondral bone until fat oozes out, stimulating fibrocartilage formation that, while not true hyaline cartilage, provides good stability and protects the surrounding surface; it should not be used for larger defects. For defects of 6 to 10 mm or more, osteochondral autograft transfer (OATS) takes a plug of cartilage and bone from a non-weight-bearing part of the knee and press-fits it into the prepared defect in a single-stage procedure, healing in 6 to 8 weeks with very rare donor site problems, up to a maximum graft size of around 20 mm.
Autologous chondrocyte implantation and synthetic scaffolds
For very large defects, or when there is not enough tissue available for an OATS graft, autologous chondrocyte implantation (ACI) is the option: cartilage cells are collected in a first surgery, grown and multiplied in a laboratory over about six weeks, then implanted in a second surgery, producing true hyaline cartilage rather than fibrocartilage, at the cost of requiring two operations. Patients who prefer a single procedure can instead be treated with collagen matrix or osteochondral scaffolds from allograft or synthetic sources, secured with tissue adhesive, which form fibrocartilage over time. Tissue engineering, fabricating cartilage tissue in a laboratory for use as a graft, is the next frontier and not yet freely available in India.
This article is based on a Jivo Masterclass session conducted by Dr. Vipin Maheshwari, Senior Consultant, Orthopaedics, Artemis Hospitals, Gurugram. The article has been summarised with the assistance of an AI tool from the original masterclass recording. Watch the full Masterclass recording
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This guide is based on a live Jivo Masterclass — Dr. Vipin Maheshwari taught doctors across Africa on August 30, 2026.
FROM THE LIVE Q&A
Host (Varun, Jivo Healthcare)
With gym and fitness-related injuries increasingly common, which exercises carry the most risk for knees and shoulders?
Dr. Vipin Maheshwari
For the knee, heavily loaded squats, especially with all the focus on upper body and inadequate lower limb conditioning, high-speed incline treadmill running, twisting exercises on a disc twister, and overloaded quadriceps extension machines are the most common causes of ACL ruptures and quadriceps or patellar tendon injuries. For the shoulder, wide-grip flies taken too far posteriorly can stress the joint, especially in anyone with a prior subluxation history. The most important message is to stop when the body signals pain rather than pushing through it.
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Frequently Asked Questions
What indicators should doctor partners in Africa and Central Asia watch for that would prompt a specialist opinion?▼
A thorough history of the mechanism of injury tells a doctor about 70% of what they need to know, since mild pain from ordinary walking is very different from a pop felt during sport followed by an immediate fall. Persistent pain despite conservative treatment should not be dismissed as non-compliance; something is usually being missed and warrants an MRI. Any significant mechanism of injury deserves a low threshold for imaging without delay, since ACL repair rather than reconstruction is possible if the patient is seen within two to three weeks of injury. Once an MRI is available and there is uncertainty about the findings, a second opinion through Jivo can confirm whether the patient needs conservative treatment, local surgery, or referral to Artemis.
What are rough cost estimates for these procedures for international patients?▼
A single ligament reconstruction, ACL or PCL, costs approximately $4,000 to $4,500, all-inclusive from admission to discharge. Meniscal debridement alone is $2,500 to $3,000, and meniscal repair ranges from $4,000 to $5,000 depending on the number of suture anchors used, at roughly $500 each. A simple Bankart repair for shoulder instability costs $4,000 to $5,000, with remplissage adding about $1,000. PRP injections without surgery run about $500 per injection, with 3 to 4 injections typically needed over roughly six weeks.
What success rates can patients realistically expect from these procedures?▼
Ligament reconstruction, ACL or PCL, has a 98 to 99% success rate, with failures very rarely seen. Meniscal repair success depends on how much of the meniscus is torn and how early the patient presents, but even large tears repaired a year after injury succeed around 90 to 95% of the time. Shoulder stabilisation surgery, Bankart repair or Latarjet, is 95 to 98% successful when planned correctly, and rotator cuff repair succeeds 90 to 95% of the time.
Why do peripheral meniscus tears have better healing potential?▼
Blood supply to the meniscus runs from outside to inside, dividing it into three zones. The outer red-red zone near the capsule has decent blood supply, which is why peripheral tears heal well. The middle red-white zone has moderate blood supply and can still be repaired if augmented with orthobiologics. The innermost white-white zone has very poor blood supply, and a peripheral rim tear there is better debrided than repaired with multiple anchors into non-vascular tissue.
Why does modern practice try to preserve meniscal tissue whenever possible?▼
The meniscus is the only shock absorber between the femur and the tibia, taking on all the compressive and shear stress of walking, running and sport, and preventing the two bones' cartilage from grinding directly against each other. Once it is removed, that cartilage-on-cartilage contact leads to arthritis within a few years. A patient can function without an ACL, but without a meniscus, arthritis is inevitable.
What is microfracture and when is it used for cartilage defects?▼
Microfracture creates small holes through the subchondral bone to stimulate fibrocartilage formation, and is used only for small defects up to 4 to 6 mm; it should not be used for larger defects.
What is the difference between OATS and autologous chondrocyte implantation (ACI)?▼
OATS is a one-stage procedure that transfers a plug of the patient's own cartilage and bone into the defect, suitable for defects of 6 to 10 mm or more up to about 20 mm. ACI is a two-stage procedure for very large defects that grows the patient's own cartilage cells in a laboratory before implanting them, producing true hyaline cartilage rather than fibrocartilage.
In This Series: Newer Advances in Arthroscopic Surgeries of Knee and Shoulder
- 1.Newer Advances in Arthroscopic Surgeries of Knee and Shoulder
- 2.ACL Reconstruction: From Traditional Tunnels to the All-Inside Technique
- 3.Internal Bracing and Synthetic Grafts in ACL Surgery
- 4.Lateral Extra-Articular Tenodesis and Why ACL Reconstructions Fail
- 5.Meniscus Repair: From Excision to Preservation
- 6.Meniscal Transplant: Restoring a Knee That Has Lost Its Meniscus
- 7.Cartilage Repair: Microfracture, OATS and Autologous Chondrocyte Implantation
- 8.Rotator Cuff Repair and Patch Augmentation
- 9.Shoulder Instability: Bankart Repair, Remplissage and Latarjet
- 10.The Future of Arthroscopy: Biology, Technology and Personalisation
- 11.Recovery Timelines, Injury Prevention and When to Refer
- 12.Cost and Success Rates for Arthroscopic Surgery at Artemis