Consultant, Surgical Oncology, Artemis Hospitals, Gurugram
Part 7 of 10 in Diagnosis and Management of Esophageal Cancer
Esophagectomy: How the Surgery Is Performed, and the Shift Toward Robotic Techniques
September 6, 2026
For patients who need surgery, esophagectomy is a demanding operation, and how it is performed, open versus minimally invasive, and laparoscopic versus robotic, has shifted substantially in recent years.
What the Operation Involves
Esophagectomy involves removing the entire length of the esophagus, from the thoracic inlet down to the gastroesophageal junction, and then reconstructing a neo-esophagus by fashioning a gastric conduit and bringing it up through the posterior mediastinal route.
Open Versus Minimally Invasive Approaches
The operation can be done as open surgery or as minimally invasive surgery, using either a laparoscopic or a robotic approach. For most cases today, a minimally invasive approach is preferred. The robotic approach in particular shows meaningfully better outcomes on several fronts at once: more precise circumferential dissection of the tumour, better oncological quality and radicality of the specimen removed, and faster early post-operative recovery for the patient.
An Option for Frail Patients
Not every patient can tolerate a full trans-thoracic esophagectomy. For a very frail patient, or one with borderline fitness, particularly where the tumour sits at the gastroesophageal junction and isn't especially bulky, a trans-hiatal esophagectomy can be offered instead, and it is better tolerated than the trans-thoracic route in exactly this group of patients.
Nutrition and Rehabilitation Are Not an Afterthought
Nutritional rehabilitation and physiotherapy for chest rehabilitation are treated as essential components of care around esophagectomy, not optional extras, given how significant a physiological stress the surgery represents, particularly in a patient population that already tends to be older and to carry multiple comorbidities.
This article is based on a Jivo Masterclass session conducted by Dr. Preeti Vijayakumaran, Consultant, Surgical Oncology, Artemis Hospital, Gurugram. The article has been summarised with the assistance of an AI tool from the original masterclass recording. Watch the full Masterclass recording
This guide is based on a live Jivo Masterclass: Dr. Preeti Vijayakumaran taught doctors across Africa on March 16, 2025.
FROM THE LIVE Q&A
Dr. Morris
What are the methods of preventing esophageal cancer?
Dr. Preeti Vijayakumaran
Prevention starts with understanding the risk factors, which depend on the histological subtype. For adenocarcinoma, the drivers can be obesity, reflux disease, and smoking and alcohol, so limiting smoking and alcohol matters, and an existing reflux disease needs to be managed medically. Patients with an already existing condition should also be started early on more stringent endoscopic surveillance. For squamous cell carcinoma, the pathology is more related to smoking and diet habits, and regulating those can make a difference.
Book a Consultation with Dr. Preeti Vijayakumaran
Book on WhatsAppOr message us on WhatsApp: +91 98182 98669
Frequently Asked Questions
Based on your experience, what do you recommend to junior doctors about such an annoying disease of our patients?▼
There is a lot of ignorance in our community, especially in our country, about a complex disease like esophageal cancer. Patients have early, subtle symptoms of difficulty swallowing, but they are often ignored and mistaken for some other common ailment. The need for awareness is foremost. As doctors, we should involve ourselves in educating more and more of the public about the disease, its diagnosis and the treatments available, so that if it is detected early, we can offer patients the maximum curative options.
In routine practice we frequently encounter cases of PPD poisoning due to suicide attempts, which lead to caustic esophageal injury resulting in chronic esophagitis. In such cases, can chronic esophagitis be considered a precancerous lesion?▼
That is a very valid question. Even in our community we see a lot of cases of caustic esophageal injury, and this chronic esophagitis can eventually lead to stricturous disease and become a predisposing cause for esophageal cancer. Patients who survive such an injury and go on to develop stricturous disease should be kept on a very stringent surveillance protocol.
Is there any specific age at which to start screening by endoscopy or another modality?▼
In our practice, screening is recommended after the age of 35 to 40 years, particularly for patients with reflux symptoms or a risk of Barrett's esophagus, though this is a variable number depending on institutional protocol. In practice, we take these patients up for endoscopic mapping: any area showing dysplastic change is biopsied. If there is no evidence of dysplasia after multiple biopsies, the patient is kept on surveillance. Low-grade dysplasia is followed up. High-grade dysplasia in a flat lesion under 2 cm is ablated, and high-grade dysplasia over 2 cm, or with a nodular appearance, is taken for endoscopic resection with histopathology follow-up on the specimen.
In this case of caustic injury from PPD poisoning, what preventive measures should be taken?▼
Most of these patients go on to develop stricturous disease, leading to significant dysphagia and a chronic inability to take oral nutrition. In such patients, an esophagectomy with a neo-esophagus is offered. In patients who do not develop stricturous disease, six-monthly endoscopic evaluation with biopsy of any suspicious area is done instead, and further imaging is not required unless a biopsy proves malignancy.
How do you differentiate gastroesophageal junction cancer and lower esophageal cancer, and the difference in their care?▼
The protocol is endoscopic mapping. The endoscopist localises exactly where the tumour sits relative to the GE junction, using a standard landmark of around 40 cm from the incisors, which varies slightly with the patient's own oesophageal length. Once that is determined, the malignancy is mapped against the gastroesophageal junction, and this is cross-checked against the axial imaging. If there is any disagreement between the endoscopic and imaging findings, the axial imaging representation is preferred to finalise the diagnosis.
What does an esophagectomy involve?▼
Removing the entire esophagus from the thoracic inlet to the gastroesophageal junction and reconstructing a neo-esophagus from a gastric conduit brought through the posterior mediastinum.
Why is the robotic approach preferred for esophagectomy?▼
It offers more precise tumour dissection, better oncological radicality of the specimen, and faster early post-operative recovery compared with open or standard laparoscopic surgery.
What is a trans-hiatal esophagectomy used for?▼
It is offered to frail or borderline-fitness patients, particularly with a non-bulky gastroesophageal junction tumour, since it is better tolerated than a trans-thoracic approach in this group.
In This Series: Diagnosis and Management of Esophageal Cancer
- 1.Diagnosis and Management of Esophageal Cancer
- 2.Early Warning Signs and Symptoms of Esophageal Cancer
- 3.How Esophageal Cancer Is Diagnosed and Staged
- 4.Telling Gastroesophageal Junction Cancer Apart From Lower Esophageal Cancer
- 5.Treating Early-Stage Esophageal Cancer: When Endoscopy Can Replace Surgery
- 6.Managing Locally Advanced Esophageal Cancer: What the Major Trials Show
- 7.Esophagectomy: How the Surgery Is Performed, and the Shift Toward Robotic Techniques
- 8.Immunotherapy in Esophageal Cancer: Where the Evidence Stands Today
- 9.Screening, Prevention and Risk Factors for Esophageal Cancer
- 10.Life After Treatment: Surveillance for Esophageal Cancer and Managing Recurrence