Obstetrics & GynaecologyDr. Archit PanditGynaecologic Oncology

Director, Surgical Oncology, Fortis Escorts, Okhla, New Delhi

Part 5 of 11 in Advanced Treatments in Gynaec Oncology

HPV Vaccination and the Prevention of Cervical Cancer

Of the four gynaecologic cancers Dr. Pandit's masterclass covers, cervical cancer is the one that can genuinely be prevented, not just caught early, because it is caused by human papillomavirus infection, and that infection can be vaccinated against.

Two established vaccines, and one made in India

Cervarix and Gardasil are the two HPV vaccines most widely recognised worldwide. India has also developed its own, Cervavac, a domestically manufactured vaccine that is considerably cheaper and now administered routinely.

Who should be vaccinated, and when

The vaccine is recommended for both boys and girls between the ages of 9 and 26, with the greatest effectiveness when given between 9 and 14, before likely exposure to the virus.

A gap seen firsthand

Dr. Pandit points to a shared risk profile between India and parts of Africa: similar socioeconomic conditions, limited sexual health education, and a correspondingly high incidence of cervical cancer. On visits to Kenya and Uganda, he found the vaccine was not widely available, and argues that general practitioners are well placed to become advocates for it in their own communities, given how directly vaccination and screening translate into fewer cervical cancer diagnoses.

Vaccination doesn't replace screening

Regular pap smear examinations and HPV testing remain part of the same prevention strategy. Any abnormal result should be followed up with a repeat test, not left unchecked, since that follow-up is what catches disease before it progresses.

This guide is based on a live Jivo Masterclass — Dr. Archit Pandit taught doctors across Africa on June 22, 2025.

FROM THE LIVE Q&A

DR

Dr. William Gadaga (Zimbabwe)

Since HIPEC is used from stage three onward, is it possible to use HIPEC or another technology to operate on a stage two cervical cancer patient?

AP

Dr. Archit Pandit

Dr. Pandit said no, HIPEC is not used for cervical cancer at all. It is limited to six cancers: peritoneal, appendiceal, ovarian, colon, rectal and some stomach cancers, and of the gynaecologic cancers, only ovarian and endometrial cancer qualify. Cervical cancer is treated with surgery in its early stages, and with chemotherapy, radiation and sometimes immunotherapy from stage 2B onward.

See all 6 questions from this masterclass →

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Frequently Asked Questions

How can general practitioners from Africa access surgical training courses at Fortis?

After clarifying the question was about medicine-side doctors rather than surgeons, Dr. Pandit said they can join as observers, since hands-on training in India is reserved for foreign doctors who are themselves surgeons or gynaecologists. Observers get an overview of cancer care spanning preventive health checkups, medical oncology and surgical oncology, and can join the hospital's tumour board, the round-table meeting where the full team reviews each case against the current world literature.

What can be done to improve overall healthcare delivery to doctors and patients across Africa?

Varun, the session host, said this reflects the underlying model of the collaboration: connecting Indian specialists using current-day technology and treatment processes with doctors across Africa to help achieve better medical outcomes, and offered to continue the conversation with Dr. Sunday directly after the session.

What is the cost range for laparoscopic surgeries for gynaecologic oncology cases, and does the hospital offer chemoradiotherapy, IMRT and VMAT?

Dr. Pandit said laparoscopic cancer surgery, including radical hysterectomy and hysterectomy, typically costs between $5,000 and $5,500, while procedures for endometriosis such as myomectomy range from $5,000 to $6,500. Fortis offers the full range of radiation oncology, including 3D-CRT, IMRT, IGRT, 3D-ARC, CyberKnife and tomotherapy, as well as brachytherapy, and has access to targeted therapy, immunotherapy and, at one centre in India, CAR-T cell therapy.

What is the utility of high-intensity focused ultrasound (HIFU) therapy for gynaecologic malignancies, is it available at your institution, and what does it cost?

Dr. Pandit said focused high-frequency ultrasound therapy is generally used for small fibroids rather than malignancy, which is his own area of focus, but confirmed Fortis does perform it, at a cost of $4,500 to $6,500.

What advancements has Fortis made for African patients with gynaecologic malignancies, and what are the most recent and frequent surgical treatments and their estimated costs?

Dr. Pandit said no treatment is specific to African patients as such, but pointed to cancer vaccination, for cervical, genital, vaginal and vulval cancers, as an area worth spreading in Africa. On surgery, he named HIPEC as the most significant advancement, now used for ovarian cancer along with peritoneal, appendiceal, colon, rectal and some stomach cancers, transforming outcomes over the last 10 to 15 years for patients previously diagnosed too late for treatment. He also pointed to robotic and laparoscopic surgery for retroperitoneal lymph node dissection, endometriosis and radical hysterectomy, and to sentinel lymph node dissection, which avoids removing the full set of pelvic lymph nodes. Surgical costs range from $5,000 to $7,000, and HIPEC surgery costs $11,000 to $12,000.

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