Chairman - Interventional Cardiology - Cardiology & Structural Heart Disease, BLK-Max Super Speciality Hospital, New Delhi, India
Part 15 of 15 in Emerging Trends in Cardiology: Advances in Minimally Invasive Interventions, TAVI
When to Treat Aortic Stenosis: The Echocardiogram Criteria Doctors Use
August 6, 2026
Aortic stenosis should be treated once the mean gradient across the aortic valve on echocardiogram exceeds 40 mm of mercury, even if the patient has no symptoms at all.
The key echocardiogram threshold
Echocardiography is the main tool used to decide when to intervene in aortic stenosis. If the mean gradient across the aortic valve is in excess of 40 mm of mercury, treatment should be considered even in a patient who feels well and has no symptoms, because the risk of dying within the next five years without treatment is very high otherwise.
Why symptoms change the urgency
In a symptomatic patient, echocardiogram findings are read alongside symptoms such as angina, syncope or breathlessness to decide on timing. Once these symptoms are present together with significant aortic stenosis on echo, treatment, whether surgical aortic valve replacement or TAVI, should not be delayed.
Why timely action matters
Aortic stenosis has no effective medical treatment: tablets cannot reverse the narrowing of the valve. This is why echocardiogram criteria such as the 40 mm mercury mean gradient threshold exist, so that doctors and patients know exactly when to act rather than waiting for the disease to progress further. Dr. Subhash Chandra of BLK-Max Super Speciality Hospital in New Delhi notes that acting on these criteria in time, through either surgery or TAVI, is what changes the outlook for a patient with aortic stenosis.
← Aortic Stenosis: Symptoms and Why Untreated Cases Are So Dangerous | Series index | What Is TAVI? Transcatheter Aortic Valve Replacement Explained →
This article is based on a Jivo Masterclass session conducted by Dr. Subhash Chandra, Chairman, Interventional Cardiology, Cardiology and Structural Heart Disease, BLK-Max Super Speciality Hospital, New Delhi, India. The article has been summarised with the assistance of an AI tool from the original masterclass recording. Watch the full Masterclass recording
This guide is based on a live Jivo Masterclass — Dr. Subhash Chandra taught doctors across Africa on January 18, 2026.
FROM THE LIVE Q&A
Dr. Innocent, Kenya
What other preventive measures are there for complications associated with TAVI, such as strokes and mortality?
Dr. Subhash Chandra
TAVI is all about planning. Doing TAVI is not a great job — it doesn't need very high level skills, but the whole energy should be dedicated to planning before you embark on the procedure. That planning is a thorough CT scan, which could be conducted locally and sent to us, and then we can plan around that CT finding as to which valve is required and what we're going to face in terms of coronary occlusion, groin complications or stroke. Mortality in TAVI can be very high if you are not careful about the groin — you should know pretty well how to manage it. The whole thing is around planning, planning, planning, planning.
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Frequently Asked Questions
What is the prognosis of SAVR versus TAVI?▼
SAVR is a very well-established technique for the last 50-plus years, and given a choice in terms of safety it should be the default choice in my opinion. Although I do TAVI quite a lot, I would still prefer a technique that is well proven and very well established — especially if the valve happens to be a bicuspid valve, a small annulus, or the patient is not very elderly. If my surgeon says the surgical risk is very high, then I chip in and accept those patients for TAVI. Though in recent trials TAVI has been established as non-inferior even for intermediate to low-risk populations, the decision should still be individualised on the merit of the patient.
If we are conducting annual screening for high-risk groups, what are the minimum tests that should be done?▼
As far as cardiology goes, the basic screening tools would be a thorough echocardiography and ECG, blood tests like lipid profiles, CRP values, and HbA1c for underlying diabetes mellitus, and sometimes even a stress test to dig out coronary artery disease. These are classical tests conducted in most people who have passed the age of 40 or 45, and especially the elderly — a thorough echocardiography usually digs out the necessary information, and then we start acting on the preventive aspect.
How can doctors join your fellowship program?▼
They should be in touch with us and send their CVs. They should be ready to face a physical interview, maybe online or coming here, and then we appraise them that they're fit to be inducted into our program. There are some local country regulatory bodies that clear their CVs — that part is also done by BLK. There are minimal fees involved, and they have to make their local arrangements for stay, food and clothing — and people have really been benefited by being with us in our lab, and we give them hands-on experience at some stage.
I have a case where a patient experienced a lump in the right hand near the palm. The heart rate is 120, pressure 110 by 90, and it comes and goes. What can be the cause?▼
It's difficult to comment on this. It could be a vascular lump or some kind of arteriovenous fistula in the palm, but one has to do a thorough CT scan, a contrast CT, or maybe a DSA, and then only one can find out as to what is the reason — and can also fix it by minimally invasive technique, putting in a covered stent or coils accordingly. But one has to first prove what we're dealing with; I can't say on this bare information.
What are the cost implications of minimally invasive surgeries like TAVI compared to traditional open surgery?▼
In India, open heart surgeries are cheaper than the West because the logistics of hospital management, bed and other things lasting six to seven days don't cost as much. Surgery is definitely cheaper here, and given that a lot of innovation goes into preparing minimally invasive procedures, those are at a slightly higher cost, or at least at par with the surgical technique. TAVI in India compared to the surgical procedure is about double the cost — in the West it could even be less than the surgical procedure, because their overheads and surgical procedures are much more expensive. In India we could offer this TAVI procedure for as little as $25,000, which could be perhaps the least in the world.
At what echocardiogram threshold should aortic stenosis be treated?▼
Treatment should be considered once the mean gradient across the aortic valve on echocardiogram exceeds 40 mm of mercury, even if the patient has no symptoms at all.
Can medication treat aortic stenosis?▼
No, aortic stenosis has no effective medical treatment because tablets cannot reverse the narrowing of the valve, which is why echocardiogram criteria exist to guide timely intervention.
How do symptoms affect the timing of aortic stenosis treatment?▼
In a symptomatic patient, echocardiogram findings are read alongside symptoms such as angina, syncope or breathlessness, and once these are present together with significant aortic stenosis on echo, treatment should not be delayed.
In This Series: Emerging Trends in Cardiology: Advances in Minimally Invasive Interventions, TAVI
- 1.Emerging Trends in Cardiology
- 2.Annual Heart Screening: The Basic Tests High-Risk Patients Should Get
- 3.Aortic Stenosis: Symptoms and Why Untreated Cases Are So Dangerous
- 4.Balloon Aortic Valvuloplasty: A Bridge to TAVI, Not a Lasting Fix
- 5.Cost of TAVI in India: Why It Is Among the Most Affordable in the World
- 6.Why a Thorough CT Scan Is the Most Important Step Before TAVI
- 7.Heart-Healthy Lifestyle: A Cardiologist's Advice on Diet and Exercise
- 8.TAVI Access Routes: Transfemoral, Subclavian, Carotid and Transcaval
- 9.TAVI Complications and How They Are Prevented
- 10.TAVI vs Surgical Aortic Valve Replacement: How Doctors Decide
- 11.TMVR: Transcatheter Mitral Valve Replacement Explained
- 12.Types of TAVI Valves: Balloon-Expandable and Self-Expanding Options
- 13.Valve-in-Valve TAVI: A Minimally Invasive Fix for a Failed Surgical Valve
- 14.What Is TAVI? Transcatheter Aortic Valve Replacement Explained
- 15.When to Treat Aortic Stenosis: The Echocardiogram Criteria Doctors Use