OrthopaedicsDr. Rakesh MahajanJoint Pain in Younger Population

Vice Chairman and Head of Department, Orthopaedics, BLK-Max Super Speciality Hospital, New Delhi, India

Part 2 of 9 in Joint Pain in the Younger Population: Causes, Prevention and Modern Treatments

Why Joint Pain Is Rising in Younger Patients: Overuse, Sedentary Life and Autoimmune Disease

May 3, 2026

Dr. Mahajan defines the younger patient group as teens to 40: an active, informed population that seeks treatment proactively rather than waiting, which makes early diagnosis both more achievable and more important, since untreated joint problems in this group progress to damage that is far harder to reverse once established.

Overuse produces a predictable pattern by activity: runners and field-sport athletes injure the foot, ankle, knee and hip; racquet-sport players injure the shoulder, elbow and wrist; fast bowlers strain the shoulder's multiple ligaments and rotator cuff; long-distance runners strain the hamstrings, Achilles tendon and hip abductors. Sedentary desk work causes a different pattern. Two to three hours of continuous screen use produces cervical and lumbar stiffness as the neck and dorsal spine's anti-gravity muscles weaken under sustained postural load, and also compounds obesity: a recent Indian survey found around 30% of young people now have a BMI above 30.

On the autoimmune side, rheumatoid arthritis, ankylosing spondylitis, hypothyroid arthropathy and juvenile arthritis all present in this age group, with morning stiffness, swelling and progressive range-of-motion loss as hallmark features. Patients on long-term steroids for these conditions develop steroid-induced osteopenia on top of the joint damage itself: a genuine vicious cycle of reduced mobility, further bone loss and rising fracture risk.

This guide is based on a live Jivo Masterclass — Dr. Rakesh Mahajan taught doctors across Africa on May 3, 2026.

FROM THE LIVE Q&A

DR

Dr. Onana Paul, Nigeria

Must all cases start with medical treatment before progressing to regenerative therapies?

RM

Dr. Rakesh Mahajan

Yes. Chronicity is labelled at 3 months, with 6 to 12 weeks as the clinical boundary. A patient should start with NSAIDs, not regenerative therapy. Only if steroid injection has also failed to control the inflammation between 6 and 12 weeks should regenerative therapy be considered, and 3 months is the ideal timing.

See all 9 questions from this masterclass →

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Frequently Asked Questions

How is PRP prepared?

Around 10 to 14 ml of blood is drawn from the patient into a kit-supplied vial containing heparin, then centrifuged to separate the platelet-rich plasma from the rest of the blood. This typically yields about 5 ml of PRP solution, which is injected as multiple pricks around the tendon or ligament rather than as a single injection, to achieve the best results.

How does PRP promote healing at the cellular level, and what growth factors such as PDGF and TGF-beta are involved?

Platelets contain multiple growth factors, including PDGF and TGF-beta, that promote healing through two mechanisms: increasing vascularisation of the target tissue and stimulating cellular regeneration. One group of factors increases local blood supply, while another increases cellular activity — together they drive ligament, tendon and articular cartilage repair.

What nutraceuticals do you recommend for joint pain treatment?

For articular cartilage involvement, collagen type 2, often combined with Boswellia, promotes cartilage cell multiplication and needs to be taken long-term. For partial tears of ligaments and tendons — which are rich in collagen type 1 and 3 — separate collagen 1 and 3 formulations are more appropriate, since they support healing of that specific tissue.

Fitness influencers push weight training for long-term bone density, but there's a real risk of injury from bad form or pushing beyond one's capacity. How do you balance that?

Go in a graded way and know your own limits — the simple principle is Young's modulus: push a muscle or tendon beyond its elastic limit and it will fail. Many young patients doing heavy weights on a gym instructor's encouragement end up damaging their elbows and shoulders. Proper training for gym instructors would prevent a lot of this. That said, if instruction is proper and progression is graded, strength training in younger years does directly help maintain bone strength into old age.

Fitness influencers often push up to 2 grams of protein per kilogram of body weight, while doctors generally recommend 0.8 to 1.5 g/kg. What is your view on overuse?

Overuse will definitely damage the kidneys, and can even cause kidney shock with permanent damage. There is also a real risk that commercial protein products are contaminated with anabolic steroids. Gym users should consult a nutritionist or dietitian to be guided on protein source and dose relative to body weight and activity level, rather than following generic online advice.

Which joints are most commonly injured in long-distance runners?

Long-distance runners typically strain the hamstrings, Achilles tendon and hip abductors, a pattern distinct from field-sport athletes, who more often injure the foot, ankle, knee and hip.

How does a sedentary desk job contribute to joint and spine pain?

Two to three hours of continuous screen use produces cervical and lumbar stiffness as the anti-gravity muscles of the neck and dorsal spine weaken under sustained postural load, and this pattern also compounds obesity.

What autoimmune conditions commonly cause joint pain in younger patients?

Rheumatoid arthritis, ankylosing spondylitis, hypothyroid arthropathy and juvenile arthritis all present in this age group, with morning stiffness, swelling and progressive loss of range of motion as hallmark features.

Why do patients on long-term steroids for autoimmune joint disease face added bone risk?

Long-term steroid use for these conditions produces steroid-induced osteopenia on top of the joint damage itself, creating a cycle of reduced mobility, further bone loss and rising fracture risk.

How common is obesity among young people, and why does it matter for joint health?

A recent survey in India found around 30% of young people now have a BMI above 30, adding mechanical load on top of the joint strain already caused by sedentary living.

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