Chief - Paediatric Cardio Thoracic and Vascular Surgery (CTVS), Artemis Hospitals, Gurgaon, India
Part 2 of 14 in Correct Timing for Congenital Heart Surgery
Atrial Septal Defect (ASD): Why the Best Age to Close It Is 3 to 4 Years
August 6, 2026
The best age to close a simple atrial septal defect is 3 to 4 years, since waiting this long does not increase the risk of death and gives the child a better tolerance to the heart-lung machine used during surgery.
What an atrial septal defect is
An atrial septal defect, or ASD, is a hole or communication between the upper collecting chambers of the heart, the right and left atrium. It is one of the most common congenital heart conditions and, unlike most other congenital heart defects, is one where waiting for the right window is actually recommended.
Why waiting until 3 to 4 years is safe
Survival data for children with an untreated atrial septal defect closely matches survival in the general population for the first three to four years of life, meaning there is no increase in mortality during this waiting period. Children are also better able to tolerate the heart-lung machine used during atrial septal defect closure once they are a little older, and closing the defect at 3 to 4 years of age is associated with normal life expectancy and quality of life, with no memory of the surgery itself.
Why delaying beyond 4 years becomes risky
If atrial septal defect closure is delayed beyond 3 to 4 years, survival curves start to decline: by 10 years a significant proportion of children with an untreated atrial septal defect do not survive, and by 20 years around 10 percent will have died, mainly from atrial fibrillation and other supraventricular arrhythmias, with right heart failure becoming the main cause of death by 30 to 40 years of age. This is why atrial septal defect closure should be carried out at 3 to 4 years, before survival curves begin sloping downward, as part of well-timed congenital heart surgery.
Series index | Ventricular Septal Defect (VSD): When Small Holes Close on Their Own and When Surgery Can't Wait →
This article is based on a Jivo Masterclass session conducted by Dr. Aseem R. Srivastava, Chief, Paediatric CTVS and Adult Congenital Heart Diseases, Artemis Hospitals, Gurgaon, India. The article has been summarised with the assistance of an AI tool from the original masterclass recording. Watch the full Masterclass recording
This guide is based on a live Jivo Masterclass — Dr. Aseem R. Srivastava taught doctors across Africa on August 31, 2025.
FROM THE LIVE Q&A
Dr. William Gataga (Zimbabwe)
What is the average cost of ASD closure?
Dr. Aseem R. Srivastava
Approximately 5,500 USD.
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Frequently Asked Questions
What is the correct timing for a patient with transposition of the great arteries (TGA), VSD, and LVOT obstruction? Also, since we live in a resource-limited country where diagnosis is sometimes made late, and patients may then ask for treatment abroad after a late diagnosis, what is your recommendation for handling late presenters, especially with simple shunt lesions?▼
For TGA with VSD and LVOT obstruction, these kids essentially have pulmonary stenosis with a VSD, and timing depends on the kid's oxygen saturation — they will need a Rastelli or a Nikaidoh operation, both requiring an implant, and the intent is to give the biggest implant possible since a smaller implant means an earlier return for a change. If saturations are above 75% and the kid is growing and doing well, they can wait and have surgery at around one year of age; if saturations are less than 75% with significant failure to thrive, they should come for surgery at any age or weight. On late presenters: we are also a resource-limited country — four or five surgeons doing this work for half of India — and face the same problem of kids coming late every day. My suggestion is education programmes, including pulse oximeter screening at birth, 1 month, and 6 months, referring for an echo early if abnormal. Late-presenting PDAs and cyanotic conditions apart from TGA are usually still operable, even if at slightly higher risk, but VSD shunt lesions can become inoperable if too late — however, even when a kid looks clinically inoperable, we always offer a cardiac catheterisation to confirm, since a significant proportion will still turn out to be operable, if high risk. And even an inoperable VSD child, with good, appropriately timed medical management (diuretics, pulmonary vasodilators), can still survive 25–35 years, whereas without that care they will die much earlier.
What is the average cost of ASD closure?▼
Approximately 5,500 USD.
What is the best age to close an atrial septal defect?▼
3 to 4 years of age. Waiting until this age does not increase the risk of death and gives the child better tolerance to the heart-lung machine used during closure.
Why is it safe to wait to close an atrial septal defect until a child is 3 to 4 years old?▼
Survival data for children with an untreated ASD closely matches survival in the general population for the first three to four years of life, so there is no increase in mortality during this window. Children also tolerate the heart-lung machine used in closure better once they are a little older.
What happens if ASD closure is delayed beyond 4 years of age?▼
Survival curves start to decline. By 10 years, a significant proportion of children with an untreated ASD do not survive, and by 20 years around 10 percent will have died, mainly from atrial fibrillation and other supraventricular arrhythmias, with right heart failure becoming the leading cause of death by 30 to 40 years of age.
What is an atrial septal defect?▼
A hole or communication between the heart's upper collecting chambers, the right and left atrium. It is one of the most common congenital heart conditions.
Does closing an ASD at 3 to 4 years affect a child's long-term quality of life?▼
No. Closure at this age is associated with normal life expectancy and quality of life, and children retain no memory of the surgery itself.
In This Series: Correct Timing for Congenital Heart Surgery
- 1.Correct Timing for Congenital Heart Surgery
- 2.Atrial Septal Defect (ASD): Why the Best Age to Close It Is 3 to 4 Years
- 3.AV Canal Defect: Why Surgery Is Needed by 3 to 4 Months of Age
- 4.Coarctation of the Aorta: Why Immediate Surgery Prevents Death and Lifelong Hypertension
- 5.Cost of Congenital Heart Surgery in India
- 6.Late-Presenting Congenital Heart Disease: What to Do When Diagnosis Comes Too Late
- 7.What Makes a Good Paediatric Cardiac Surgery Programme
- 8.Patent Ductus Arteriosus (PDA): When to Close and How
- 9.Total Anomalous Pulmonary Venous Return (TAPVR): Why Surgery Cannot Wait
- 10.Tetralogy of Fallot: Timing of Repair and Why Waiting Is Dangerous
- 11.Transposition of the Great Arteries (TGA): Why Timing Is a Matter of Days
- 12.TGA with VSD and Pulmonary Stenosis: Rastelli and Nikaidoh Procedures
- 13.Truncus Arteriosus: Why Newborns Need Surgery at Diagnosis
- 14.Ventricular Septal Defect (VSD): When Small Holes Close on Their Own and When Surgery Can't Wait