NeurosurgeryDr. Anil Kumar KansalBrain & Spine Surgery

Vice Chairman and HOD, Neuro Surgery and Neuro Spine, BLK-Max Super Speciality Hospital, New Delhi, India

Part 9 of 17 in Recent Advances in Neurosurgery

Gamma Knife Radiosurgery for Brain Tumours

August 6, 2026

Gamma knife radiosurgery delivers a single, precisely targeted dose of radiation to small brain tumours such as meningiomas and metastases, avoiding open surgery altogether in many suitable cases.

What gamma knife treats

Gamma knife radiosurgery is used for small tumours including meningiomas, pituitary tumours, arteriovenous malformations, metastatic lesions and recurrent tumours. It is particularly useful for tumours in locations such as the cavernous sinus, small cerebellopontine angle tumours, and other deep-seated or metastatic brain tumours that are limited in number.

How gamma knife works

Gamma knife delivers a single dose of radiation precisely targeted at the tumour, effectively burning the tumour tissue without the need for an open surgical procedure. In many suitable cases, this allows quite extensive tumour surgery to be avoided altogether.

Advantages of gamma knife radiosurgery

As a form of radiosurgery, gamma knife is non-surgical and non-invasive, and unlike some older techniques, no head frame is required. Cancer control is good, treatment usually requires only one or two sessions, and patients generally do well afterwards. This makes gamma knife an important option within neurosurgery in India for patients with small, well-defined brain tumours who want to avoid open surgery.

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This article is based on a Jivo Masterclass session conducted by Dr. Anil Kumar Kansal, Vice Chairman and HOD, Neurosurgery and Neuro Spine Department, BLK-Max Super Speciality Hospital, New Delhi. The article has been summarised with the assistance of an AI tool from the original masterclass recording. Watch the full Masterclass recording

This guide is based on a live Jivo Masterclass — Dr. Anil Kumar Kansal taught doctors across Africa on July 13, 2025.

FROM THE LIVE Q&A

DR

Dr. Ashettu (Ethiopia)

Are there any recent advances in the management of paediatric congenital hydrocephalus?

AK

Dr. Anil Kumar Kansal

We do endoscopic third ventriculostomy in paediatric congenital hydrocephalus, but success is slightly lower at a young age — around 70-80%. A programmable shunt has a 95% success rate, but shunt revision and infection are other factors to weigh; endoscopic third ventriculostomy is a better choice when it succeeds, since the chances of recurrence problems afterward are very low.

See all 6 questions from this masterclass →

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Frequently Asked Questions

What is the time needed for full recovery, and what are the complications, for trigeminal neuralgia treatment (microvascular decompression)?

We keep the patient for three or four days; the pain is usually gone right after surgery. We continue medication for one month afterward and then stop it. We mobilise the patient to walk from the next day, and they generally do very well. We do a post-operative CT scan to check for any bleeding or collection, but results are close to perfect.

What is the success rate of the surgery, what are the financial implications, and are the screws inserted in robotic spine surgery absorbable or will they need to be removed post-op?

The screws used in spine surgery are not absorbable — they remain in place lifelong. Financially, robotic-assisted spine surgery costs about $1,000 to $2,000 extra on top of a normal spine surgery of around $7,000, but the advantage is that screw misplacement drops to less than 1%, which is significant because a single misplaced screw can undermine the whole surgery — so while it adds cost, it also adds real value to the outcome.

What are the success rates of these surgical procedures generally, and what are the absolute contraindications to surgery?

Absolute contraindications include cardiac problems, any bleeding or coagulation disorders, or severe infection in the body. If a patient — for example with trigeminal neuralgia — is responding well to medication at a controllable dose, we will not operate; surgery is offered when the patient's pain is not relieved despite medical management.

What complications are expected from trigeminal neuralgia surgery (microvascular decompression)?

There can be anaesthesia-related complications. On the surgical side, we can get a haematoma in the cerebellum, sometimes bleeding, sometimes infection, or damage to the nerves — though our infection rate is very low. One patient developed chemical meningitis leading to hydrocephalus and needed a shunt, but the rest did very well. Initially some patients complained of partial hearing loss from traction on the eighth nerve; now we use minimal traction, so results are good and complications are minimal.

What is the recurrence rate of the tumours (in cases treated with microvascular decompression / related skull-base surgery)?

Only about 5%, not more than that. In our setup we have done more than 100 surgeries and have not had to redo any; some patients may have mild symptoms that can be managed with medicine or reassurance, but otherwise the results are good.

What conditions can gamma knife radiosurgery treat?

Small tumours including meningiomas, pituitary tumours, arteriovenous malformations, metastatic lesions and recurrent tumours, particularly those in locations such as the cavernous sinus or small cerebellopontine angle tumours.

How does gamma knife radiosurgery work?

It delivers a single dose of radiation precisely targeted at the tumour, burning the tumour tissue without an open surgical procedure, which in many suitable cases avoids extensive tumour surgery altogether.

What are the advantages of gamma knife over conventional surgery?

It is non-surgical and non-invasive, requires no head frame, offers good cancer control, and usually needs only one or two treatment sessions.

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