NeurosurgeryDr. Anil Kumar KansalBrain & Spine Surgery

Vice Chairman and HOD, Neuro Surgery and Neuro Spine, BLK-Max Super Speciality Hospital, New Delhi, India

Part 17 of 17 in Recent Advances in Neurosurgery

Trigeminal Neuralgia: Causes, Diagnosis and Treatment Options

August 6, 2026

Trigeminal neuralgia causes severe, disabling facial pain that is not life-threatening but can make everyday activities such as eating, shaving and brushing teeth extremely difficult, and is diagnosed with a detailed clinical history plus a high-quality MRI with CISS sequences.

What trigeminal neuralgia feels like

Trigeminal neuralgia causes severe pain in specific areas of the face, corresponding to the three branches of the trigeminal nerve, near the eyelid, below the eye, or elsewhere on the face, and in rare cases even the tongue. The pain can be triggered by simple activities such as shaving, brushing teeth, drinking or eating, and even a cold sensation or air on the face can trigger a severe attack, making daily life extremely difficult for patients with trigeminal neuralgia.

How trigeminal neuralgia is diagnosed

Diagnosis of trigeminal neuralgia starts clinically, based on the pattern and triggers of the pain, and is confirmed with a good-quality MRI using CISS sequences, which can show the vascular loops that are often the underlying cause. Finding and localising these vascular loops on imaging is important for planning treatment.

What causes trigeminal neuralgia

In most cases, trigeminal neuralgia is caused by a blood vessel, often a vein or artery, forming a loop that compresses the trigeminal nerve and causes demyelination, though tumours and compression from other causes can also be responsible.

Comparing treatment options

Medication is tried first for trigeminal neuralgia, but sometimes requires a very high dose to control the pain, which brings its own side effects, and in some patients the pain does not respond to medicine at all. Other options that have been tried include radiofrequency ablation and glycerol injections, which relieve numbness on the face in 50 to 20 percent of cases but often see pain return within 6 months to a year, and gamma knife radiosurgery, which takes a long time to work and only partially relieves pain. Because of these limited results, microvascular decompression surgery is now the preferred option, with around 95 percent of patients becoming pain-free and this success considered close to a permanent cure.

← Neuronavigation and Fluorescence-Guided Brain Tumour Surgery | Series index | Microvascular Decompression Surgery for Trigeminal Neuralgia →

This article is based on a Jivo Masterclass session conducted by Dr. Anil Kumar Kansal, Vice Chairman and HOD, Neurosurgery and Neuro Spine Department, BLK-Max Super Speciality Hospital, New Delhi. The article has been summarised with the assistance of an AI tool from the original masterclass recording. Watch the full Masterclass recording

This guide is based on a live Jivo Masterclass — Dr. Anil Kumar Kansal taught doctors across Africa on July 13, 2025.

FROM THE LIVE Q&A

DR

Dr. Atanda Solomon (Lagos, Nigeria)

What is the success rate of the surgery, what are the financial implications, and are the screws inserted in robotic spine surgery absorbable or will they need to be removed post-op?

AK

Dr. Anil Kumar Kansal

The screws used in spine surgery are not absorbable — they remain in place lifelong. Financially, robotic-assisted spine surgery costs about $1,000 to $2,000 extra on top of a normal spine surgery of around $7,000, but the advantage is that screw misplacement drops to less than 1%, which is significant because a single misplaced screw can undermine the whole surgery — so while it adds cost, it also adds real value to the outcome.

See all 6 questions from this masterclass →

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Frequently Asked Questions

What are the success rates of these surgical procedures generally, and what are the absolute contraindications to surgery?

Absolute contraindications include cardiac problems, any bleeding or coagulation disorders, or severe infection in the body. If a patient — for example with trigeminal neuralgia — is responding well to medication at a controllable dose, we will not operate; surgery is offered when the patient's pain is not relieved despite medical management.

What complications are expected from trigeminal neuralgia surgery (microvascular decompression)?

There can be anaesthesia-related complications. On the surgical side, we can get a haematoma in the cerebellum, sometimes bleeding, sometimes infection, or damage to the nerves — though our infection rate is very low. One patient developed chemical meningitis leading to hydrocephalus and needed a shunt, but the rest did very well. Initially some patients complained of partial hearing loss from traction on the eighth nerve; now we use minimal traction, so results are good and complications are minimal.

What is the recurrence rate of the tumours (in cases treated with microvascular decompression / related skull-base surgery)?

Only about 5%, not more than that. In our setup we have done more than 100 surgeries and have not had to redo any; some patients may have mild symptoms that can be managed with medicine or reassurance, but otherwise the results are good.

Are there any recent advances in the management of paediatric congenital hydrocephalus?

We do endoscopic third ventriculostomy in paediatric congenital hydrocephalus, but success is slightly lower at a young age — around 70-80%. A programmable shunt has a 95% success rate, but shunt revision and infection are other factors to weigh; endoscopic third ventriculostomy is a better choice when it succeeds, since the chances of recurrence problems afterward are very low.

What is the time needed for full recovery, and what are the complications, for trigeminal neuralgia treatment (microvascular decompression)?

We keep the patient for three or four days; the pain is usually gone right after surgery. We continue medication for one month afterward and then stop it. We mobilise the patient to walk from the next day, and they generally do very well. We do a post-operative CT scan to check for any bleeding or collection, but results are close to perfect.

What does trigeminal neuralgia pain feel like?

Severe pain in specific facial areas corresponding to the branches of the trigeminal nerve, near the eyelid, below the eye, or elsewhere, and in rare cases the tongue, often triggered by shaving, brushing teeth, eating, drinking or even cold air.

What causes trigeminal neuralgia?

In most cases a blood vessel, often a vein or artery, forms a loop that compresses the trigeminal nerve and causes demyelination, though tumours and other compression can also be responsible.

How is trigeminal neuralgia diagnosed?

Diagnosis starts clinically, based on the pattern and triggers of the pain, and is confirmed with a good-quality MRI using CISS sequences, which can show the vascular loops that are often the underlying cause.

How effective are non-surgical treatments for trigeminal neuralgia?

Radiofrequency ablation and glycerol injections relieve numbness in 50 to 20 percent of cases but pain often returns within six months to a year, and gamma knife radiosurgery takes a long time to work and only partially relieves pain, which is why microvascular decompression has become the preferred option.

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