OrthopaedicsDr. Ishwar BohraDegenerative Joint Disease

Senior Director, Joint Replacement Programme, BLK-Max Super Speciality Hospital, New Delhi

Part 3 of 9 in Diagnosis & Management of Degenerative Joint Disease

Managing Early Osteoarthritis Without Surgery: Lifestyle, Bracing and Medication

September 6, 2026

Not every patient with degenerative joint disease needs an operation, and Dr. Ishwar Bohra was explicit with the doctors on his Jivo Healthcare masterclass that the first line of treatment sits entirely within a GP's own toolkit: weight, exercise and support.

Start with what the patient can change

Of the risk factors for osteoarthritis, weight, exercise habits and joint support are the only ones a patient can modify directly. Dr. Bohra prioritises weight management with nutritional referral above everything else, followed by a physiotherapy programme built around quadriceps strengthening, range-of-motion exercises, swimming and cycling, all of which protect the hip, knee and shoulder without loading the joint the way running or high-impact sport does.

Braces, canes and offloading devices

For patients with more advanced but still non-surgical arthritis, a cane or walker for a short period gives the joint enough rest to settle from an acute inflammatory flare. Offloader braces, of which Dr. Bohra showed several varieties during the session, shift weight away from the damaged side of the joint, whether the deformity is a bowed or knock-kneed alignment, and can delay the need for surgery meaningfully.

The medication ladder

Drug therapy follows a stepped approach. Nutraceuticals such as glucosamine, chondroitin, MSM and various collagen preparations are marketed to strengthen cartilage, though new products in this category continue to arrive regularly. Analgesics, from acetaminophen to COX inhibitors and, where needed, opioids, manage pain directly. For patients who need more than oral medication, intra-articular injections, including hyaluronic acid, platelet-rich plasma, and ozone or oxygen therapy, are reserved for early-stage disease rather than advanced arthritis.

Knowing when this ladder has been exhausted

Dr. Bohra was clear that this entire non-surgical pathway, lifestyle change, bracing and medication together, is a bridge rather than a permanent solution for patients whose arthritis is progressing. The point at which alignment surgery, partial replacement or total replacement becomes the right recommendation is covered in the next article in this series.

This guide is based on a live Jivo Masterclass: Dr. Ishwar Bohra taught doctors across Africa on April 27, 2025.

FROM THE LIVE Q&A

DR

Dr. Olimei

Is there any risk of malignant transformation in a patient with a malunited tibia fracture of more than 10 years' duration without treatment?

IB

Dr. Ishwar Bohra

No, a malunited fracture carries no risk of malignant transformation.

See all 4 questions from this masterclass →

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Frequently Asked Questions

What is the total cost of doing a total knee replacement, in dollars?

Approximate cost in my own practice runs around 7,000 to 7,500 US dollars, depending on the patient's room selection and other choices. India, and our hospital specifically, offers one of the most subsidised rates in the world compared with the West and the rest of Asia.

Is there a relationship between vitamin D deficiency and osteoarthritis?

Definitely, because vitamin D is essential in bone metabolism: it regulates the calcium, magnesium and phosphorus that are the key minerals of bone strength. If vitamin D is low, the subchondral bone that gives cartilage its strength becomes weak, so the cartilage starts to wear and the bone becomes soft and malaligned, which leads to arthritis. This is a major contributory factor that often isn't picked up clinically, so once a patient is diagnosed with hypovitaminosis D, it should be corrected immediately to avoid future complications.

Is total knee replacement indicated for children with juvenile idiopathic arthritis?

Hip replacement can be done even after 13 to 14 years of age, but knee replacement has to wait until 18, because the longevity of implants in children is not very good and outcomes are worse than with hip replacement. If a child is severely affected, knee replacement can be considered after age 16 to 18; before that, an alternative non-replacement approach, such as bracing, is used to manage the pain.

Is there any risk of malignant transformation in a patient with a malunited tibia fracture of more than 10 years' duration without treatment?

No, a malunited fracture carries no risk of malignant transformation.

What lifestyle changes help manage early osteoarthritis?

Weight management with nutritional support, and a physiotherapy programme built around quadriceps strengthening, range-of-motion exercises, swimming and cycling.

What do offloader braces do?

They shift weight away from the damaged side of the joint, whether the deformity bows the knee inward or outward, and can meaningfully delay the need for surgery.

What medications are used for early-stage osteoarthritis?

Nutraceuticals such as glucosamine, chondroitin, MSM and collagen; analgesics including acetaminophen, COX inhibitors and opioids; and intra-articular injections such as hyaluronic acid, PRP, or ozone and oxygen therapy.

Are intra-articular injections used for advanced arthritis?

No. Dr. Bohra reserves hyaluronic acid, PRP and ozone or oxygen injections for early-stage disease, not advanced arthritis.

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