Senior Director, Joint Replacement Programme, BLK-Max Super Speciality Hospital, New Delhi
Part 7 of 9 in Diagnosis & Management of Degenerative Joint Disease
Complex and Infected Joint Replacement Cases: What a Revision Surgery Actually Involves
September 6, 2026
Some of the most demanding work in joint replacement happens after a first surgery has already failed somewhere else, and Dr. Ishwar Bohra used several real cases from his own operating theatre to show the doctors on his Jivo Healthcare masterclass what that work actually involves.
When an implant becomes infected
In one case Dr. Bohra described, a patient arrived with both joints infected after surgery performed elsewhere, a rare and especially difficult presentation. His team identified the causative bacteria, removed all of the existing implants, treated the patient with intravenous antibiotics for several weeks, and only then carried out the final reconstructive surgery. The patient took around six months to fully recover but, in Dr. Bohra's account, she ended up perfectly well. His message to referring doctors: an infection after joint replacement is not a reason to give up on the patient, but it is a reason to refer them to a centre equipped to handle it.
Failed replacements from elsewhere
Dr. Bohra also described a patient from Tanzania whose primary hip replacement, performed at another facility, failed and loosened; his team carried out a revision hip replacement with new reconstruction, and the patient was later shown, in a follow-up video from the session, dancing. Revision hip cases like this often require special implants, including long stems and extra supplementary components on the cup or femoral side, to compensate for bone that has weakened around a failed original implant.
Neglected and structurally complex cases
Patients who go years without treatment present some of the hardest cases. Dr. Bohra showed one such patient with a subluxated knee joint who had become wheelchair-bound and developed osteoporotic bone, requiring a special implant with extension rods and a hinge joint. He also described his heaviest joint replacement patient to date, at 142 kilograms, who was barely able to walk before surgery. A periprosthetic fracture, in which a patient suffers an accident after an earlier replacement, is another recurring complication that requires a further, more complex reconstructive procedure rather than a routine repeat replacement.
What separates these cases from routine surgery
Dr. Bohra told the doctors on the call that the surgery itself is rarely the hardest part of these cases. Maintaining a sterile operating environment, controlling infection risk down to close to zero, and having the judgement to plan a staged, multi-step reconstruction are what he pointed to as the real requirements for managing complex and revision joint replacement safely.
This guide is based on a live Jivo Masterclass: Dr. Ishwar Bohra taught doctors across Africa on April 27, 2025.
FROM THE LIVE Q&A
Dr. Olimei
Is there any risk of malignant transformation in a patient with a malunited tibia fracture of more than 10 years' duration without treatment?
Dr. Ishwar Bohra
No, a malunited fracture carries no risk of malignant transformation.
Frequently Asked Questions
What is the total cost of doing a total knee replacement, in dollars?▼
Approximate cost in my own practice runs around 7,000 to 7,500 US dollars, depending on the patient's room selection and other choices. India, and our hospital specifically, offers one of the most subsidised rates in the world compared with the West and the rest of Asia.
Is there a relationship between vitamin D deficiency and osteoarthritis?▼
Definitely, because vitamin D is essential in bone metabolism: it regulates the calcium, magnesium and phosphorus that are the key minerals of bone strength. If vitamin D is low, the subchondral bone that gives cartilage its strength becomes weak, so the cartilage starts to wear and the bone becomes soft and malaligned, which leads to arthritis. This is a major contributory factor that often isn't picked up clinically, so once a patient is diagnosed with hypovitaminosis D, it should be corrected immediately to avoid future complications.
Is total knee replacement indicated for children with juvenile idiopathic arthritis?▼
Hip replacement can be done even after 13 to 14 years of age, but knee replacement has to wait until 18, because the longevity of implants in children is not very good and outcomes are worse than with hip replacement. If a child is severely affected, knee replacement can be considered after age 16 to 18; before that, an alternative non-replacement approach, such as bracing, is used to manage the pain.
Is there any risk of malignant transformation in a patient with a malunited tibia fracture of more than 10 years' duration without treatment?▼
No, a malunited fracture carries no risk of malignant transformation.
How is an infected joint replacement managed?▼
The causative bacteria is identified, all existing implants are removed, intravenous antibiotics are given for several weeks, and a final reconstructive surgery follows once the infection has cleared.
What does revision hip replacement involve when a previous surgery has failed?▼
Special implants, including long stems and additional supplementary components on the cup or femoral side, to compensate for bone that has weakened around the failed original implant.
What is a periprosthetic fracture?▼
A fracture that occurs after an earlier joint replacement, typically following an accident, requiring a further complex reconstructive procedure.
What makes complex revision joint replacement cases different from routine surgery?▼
Maintaining a sterile operating environment, controlling infection risk, and planning a staged multi-step reconstruction, rather than the technical surgery alone.
In This Series: Diagnosis & Management of Degenerative Joint Disease
- 1.Diagnosis and Management of Degenerative Joint Disease
- 2.Degenerative Joint Disease: Risk Factors and How to Diagnose It in Clinic
- 3.Managing Early Osteoarthritis Without Surgery: Lifestyle, Bracing and Medication
- 4.High Tibial Osteotomy and Partial Knee Replacement: Preserving the Joint Before Full Replacement
- 5.Total Knee Replacement for Advanced Osteoarthritis: Indications and Long-Term Survival
- 6.Robotic Joint Replacement: Closing the Gap Between a Working Knee and a Happy Patient
- 7.Complex and Infected Joint Replacement Cases: What a Revision Surgery Actually Involves
- 8.Beyond the Knee: Hip, Shoulder and Elbow Replacement in Degenerative Joint Disease
- 9.The Real Cost of Total Knee Replacement in India