Consultant - Heart & Lung Transplant and Vascular Surgery, Artemis Hospitals, Gurgaon
Part 7 of 9 in Vascular Surgical Problems: From the GP's Clinic to the Specialist's Office
Pulmonary Embolism: From the Inari FlowTriever to Pulmonary Endarterectomy
May 10, 2026
On CT pulmonary angiography, a central occlusion at the bifurcation of the main pulmonary artery is called a saddle thrombus, for its resemblance to a horse's saddle; branch emboli instead block the right and left pulmonary artery branches separately. One of the most effective interventional devices available is the Inari FlowTriever, which engages the clot, locks it into a disc mechanism, and extracts it through a combination of mechanical maceration and suction.
The gold-standard treatment worldwide, however, remains surgical: pulmonary endarterectomy. It requires cardiopulmonary bypass, cooling the body to 18–20°C, and roughly 30 to 45 minutes of circulatory arrest to remove the organised clot from the pulmonary arterial tree, after which lung function, pulmonary pressures and right heart function all recover dramatically within days. Dr. Purkayastha trained at a centre specially recognised in the STS guidelines as the largest pulmonary endarterectomy centre outside the United States, and notes that ECMO-capable postoperative support makes the surgery accessible even for the highest-risk cases.
This guide is based on a live Jivo Masterclass — Dr. Biswarup Purkayastha taught doctors across Africa on May 10, 2026.
FROM THE LIVE Q&A
Host (Varun, Jivo Healthcare)
You mentioned a case where a patient initially appeared to have an arterial pain problem but ultimately did not need a vascular intervention. Can you say more?
Dr. Biswarup Purkayastha
It is a vascular disease, but the vascular problem is not what is causing the pain in this elderly lady — and if medicines can manage the condition, there is no need to intervene, even if that is commercially a loss rather than a win. There has been a silent shift from a doctor-patient relationship to a doctor-hospital relationship, where a patient's data no longer stays with the treating doctor once they change hospitals. Old-school medicine — operating only when needed, never when not needed — is what should endure through that change.
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Frequently Asked Questions
This is similar to a past case where eye pain turned out to be a neurosurgical problem — the presenting complaint pointed one way but the real cause was elsewhere. You made a related point about not confusing varicose veins with cellulitis.▼
Never confuse varicose veins with cellulitis and simply give a course of antibiotics to send the patient away — that is the wrongest possible thing to do, and it is not a constructed scenario. This happens regularly in real-life GP clinics, and any swollen leg deserves at least a Doppler ultrasound before it is written off as a skin infection.
How does the quality of the information a referring doctor sends you change the outcome for the patient?▼
Out of roughly 25 healthcare facilitators sending referrals, only one or two send a report in a structured format. A recent case arrived with mismatched patient names, ages and even genders across different files for what turned out to be the same patient — a PDF here, a broken image file there, no consolidated record. I would rather give no advice than wrong advice built on poorly collated information.
Can a patient with DVT have a normal D-dimer?▼
Absolutely, yes — particularly if the D-dimer is done after the acute phase, in a subacute presentation of a few days. Despite the test's high sensitivity, the result can come back in the low hundreds, nowhere near diagnostic. DVT is an anatomical problem, and for an anatomical problem the answer is to see it directly on ultrasound, not infer it from a blood marker. Vascular ultrasound is learnable within three to four months, and we train nearly all our trainees to do it routinely.
What are the key prognostic factors for endovascular laser ablation of varicose veins?▼
Laser ablation for superficial spider veins or one or two perforators has an excellent prognosis, and works well up to the perforator level. But if the saphenofemoral junction itself is regurgitant, open surgery to ligate the SFJ and clip the draining tributaries is usually the better option rather than relying on endovascular ablation alone.
A 78-year-old patient has arterial disease in the below-knee territory. Some doctors suggested angioplasty, while top vascular surgeons felt nothing needed to be done and that intervention carried risk. What is your view?▼
In a fragile patient, angioplasty is best avoided below the knee — it gives reasonable short-term results but nothing very promising long-term. If intervention is genuinely needed, it is more often approached surgically, favouring a reverse femoro-tibial bypass using the patient's own saphenous vein over a prosthetic graft, and favouring open surgery over an endovascular approach in this territory. Below the knee: use the simpler, older, better-proven option, and know when not to intervene at all.
What is a saddle thrombus in pulmonary embolism?▼
A central clot occluding the pulmonary artery right at the point where it bifurcates into the right and left pulmonary arteries, named for its resemblance to a horse's saddle.
How does the Inari FlowTriever treat pulmonary embolism?▼
It engages the clot and locks it into a disc mechanism, then extracts it through a combination of mechanical maceration, breaking the clot into smaller pieces, and suction.
What is the gold-standard treatment for pulmonary embolism?▼
Pulmonary endarterectomy, a surgical procedure performed on cardiopulmonary bypass with the body cooled to 18 to 20 degrees Celsius and roughly 30 to 45 minutes of circulatory arrest to remove the clot from the pulmonary arterial tree.
How quickly do patients recover after pulmonary endarterectomy?▼
Lung function, pulmonary artery pressures and right heart function typically improve dramatically within a couple of days after surgery.
In This Series: Vascular Surgical Problems: From the GP's Clinic to the Specialist's Office
- 1.Vascular Surgical Problems: From the GP's Clinic to the Specialist's Office — A Complete Guide
- 2.The Image Comes First: How to Refer a Vascular Case to a Specialist
- 3.Peripheral Arterial Disease: Medical Management Before the Scalpel
- 4.Aneurysms: Why the CT Angiogram Matters More Than the Radiology Report
- 5.Varicose Veins and the CEAP Classification: What Every GP Should Know
- 6.Why D-Dimer Is the Wrong Test for Deep Vein Thrombosis
- 7.Pulmonary Embolism: From the Inari FlowTriever to Pulmonary Endarterectomy
- 8.Anticoagulation for DVT: Rivaroxaban, Apixaban and the ABCDs of Dose Adjustment
- 9.Knowing When Not to Operate: A Vascular Surgeon's Case for Restraint