Obstetrics & GynaecologyDr. Supriya MalhotraUterine Fibroids

Obstetrician & Gynaecologist, Fortis La Femme, New Delhi

Part 2 of 9 in Prevalence, Symptoms, Diagnosis and Treatment of Uterine Fibroids

What Are Uterine Fibroids and Who Gets Them

December 14, 2025

Uterine fibroids, also called myomas or leiomyomas, are extremely common: they occur in nearly 70% of women by the age of 50 and are most frequently diagnosed between the ages of 30 and 50, the years when estrogen and progesterone are most active on the uterus. Many fibroids cause no symptoms at all and are found incidentally during a routine examination, an ultrasound for another condition, or in pregnancy.

What raises the risk

A family history of fibroids is one of the strongest risk factors: if a mother has fibroids, her daughter is considerably more likely to develop them too. An early first period increases lifetime exposure to estrogen and progesterone and raises risk further, and this is being seen more often as girls as young as 8 to 10 start menstruating earlier than in the past. Obesity and lifestyle factors such as diabetes and hypertension are also implicated, since fat tissue itself produces additional estrogen that acts on the uterus. Ethnic background plays a significant role too: fibroids are more common, grow larger, and tend to be more severe among women of African descent.

The four types, by location

Fibroids are classified by where they grow within the uterine wall. Intramural fibroids, the most common type, start and remain within the muscle layer of the uterus. Subserosal fibroids grow outward from the muscle toward the outside of the uterus and can eventually project into the abdomen as they enlarge. Submucosal fibroids grow inward toward the uterine lining and cavity, and are most closely associated with heavy bleeding and fertility problems because they physically occupy the space where an embryo would implant. Occasionally a fibroid develops a narrow stalk connecting it to the uterus, known as a pedunculated fibroid. Size varies enormously, from a small seedling to a mass as large as a watermelon.

This article is based on a Jivo Masterclass session conducted by Dr. Supriya Malhotra, Obstetrician & Gynaecologist, Fortis La Femme, New Delhi. The article has been summarised with the assistance of an AI tool from the original masterclass recording. Watch the full Masterclass recording

Looking for a diagnosis or a second opinion on uterine fibroids? Get in touch with the Jivo team

This guide is based on a live Jivo Masterclass — Dr. Supriya Malhotra taught doctors across Africa on December 14, 2025.

FROM THE LIVE Q&A

DR

Dr. Chucks (Nigeria)

How long after a myomectomy should a woman expect to be able to conceive?

SM

Dr. Supriya Malhotra

It depends on whether the myometrium was opened. If it was a laparoscopic myomectomy for a subserous, pedunculated fibroid where the myometrium was not opened, pregnancy can usually be attempted after about six months. If the myometrium was opened to remove the fibroid, the advice is to wait one and a half to two years, similar to the healing time given after a previous caesarean section.

See all 12 questions from this masterclass →

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Frequently Asked Questions

How do we differentiate dyspareunia caused by a uterine fibroid from dyspareunia caused by pelvic inflammatory disease?

Dyspareunia from pelvic inflammatory disease usually comes with vaginismus, foul-smelling vaginal discharge and sometimes urinary tract symptoms. With a fibroid, the dyspareunia is not accompanied by these features. A vaginal swab sent for examination will show an infective organism in pelvic inflammatory disease, which is usually absent when a fibroid is the cause.

What are the benefits of GnRH analogues in treating fibroids?

GnRH analogues are used to shrink a fibroid before a planned myomectomy, since a smaller fibroid means less bleeding during surgery; a monthly or three-monthly dose is given for this. The second use is in a perimenopausal woman, where these hormones hasten the natural shrinkage that would occur anyway as menopause approaches, since fibroids are otherwise known to delay menopause.

At what stage should hysteroscopy be used instead of MRI?

The two are not alternatives for diagnosis. MRI is a radiological procedure with no radiation that gives a detailed, thin-sliced view of a fibroid, and it is used when there is diagnostic doubt on ultrasound, for instance the rare possibility of a cancerous change. Hysteroscopy is a minimally invasive endoscopic procedure passed through the cervix, and it is never used as an investigative tool for diagnosing a fibroid. It is a treatment modality: it is used once a fibroid or polyp inside the cavity has already been identified, so it can be removed under direct vision.

What is your perspective on meat consumption versus a plant-based diet in managing uterine fibroids?

Weight control through exercise and diet is important, since fibroids are more common in obese patients. An anti-inflammatory, broadly Mediterranean diet is recommended: plenty of green leafy vegetables, omega-3 sources like walnuts, flax seeds and olive oil, and less caffeine, alcohol and smoking. Red meat is considered inflammatory, so white meat such as fish, turkey and chicken is the better choice.

How does uterine artery embolization compare with myomectomy?

Myomectomy is a surgical procedure requiring hospitalization, done by a gynaecologist through open surgery, laparoscopy or robotically. Uterine artery embolization is an outpatient procedure done by an interventional radiologist together with a gynaecologist, who passes a catheter through the groin artery into the vessel feeding the fibroid and injects small particles to cut off its blood supply, so the fibroid shrinks over time. It is less invasive and generally preferable to myomectomy, but it has limitations: it is not suitable for very large fibroids, for fibroids with any suspicion of malignancy, or where there is an active uterine infection.

How common are uterine fibroids?

They affect nearly 70% of women by the age of 50 and are most often diagnosed between the ages of 30 and 50, though many cause no symptoms and are found incidentally.

What are the four types of uterine fibroids?

Intramural fibroids grow within the uterine muscle, subserosal fibroids grow outward toward the abdomen, submucosal fibroids grow inward into the uterine cavity, and pedunculated fibroids develop a narrow stalk connecting them to the uterus.

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