Cardiothoracic & Transplant SurgeryDr. Biswarup PurkayasthaHeart Failure & Coronary Artery Disease

Consultant - Heart & Lung Transplant and Vascular Surgery, Artemis Hospitals, Gurgaon

Part 4 of 14 in All About Heart Failure & Coronary Artery Disease in African Population: The Way Forward

The Heart Team: Why No Single Specialist Should Manage Heart Failure Alone

June 28, 2026

Heart failure cannot be managed by a cardiologist alone, a cardiac surgeon alone, a physician alone, or an intensivist alone, Dr. Purkayastha says. A functioning heart team requires a minimum of six specialties (cardiologist, cardiothoracic surgeon, respiratory physician, intensivist, general physician, and a preventive or family medicine specialist) sitting together, debating, and at times arguing their way to the best path forward for a specific patient.

The same disease looks entirely different depending on the patient in front of the team: at 43, the answer might be an open-chest total arterial coronary bypass; at 73, a different approach in a different patient; at 83, the answer may simply be optimised medical therapy and the best possible quality of remaining life. Differentiating between these is the entire purpose of the heart team.

This guide is based on a live Jivo Masterclass — Dr. Biswarup Purkayastha taught doctors across Africa on June 28, 2026.

FROM THE LIVE Q&A

JI

Jivo Doctor Partner (name unclear from transcript)

What is the primary indication for using sacubitril/valsartan, and how is it dosed?

BP

Dr. Biswarup Purkayastha

It should be started at the lowest possible dose — half a tablet, 25mg once daily, titrated over a week to 50mg, then 100mg, not typically exceeding 100mg once daily or 50mg twice daily. The primary indication is ejection fraction below 45% with elevated NT-proBNP. In a patient with ejection fraction below 35% and high NT-proBNP, it should be initiated at the lowest dose and titrated carefully upward.

See all 9 questions from this masterclass →

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Frequently Asked Questions

From your experience, what is the relative epidemiology of coronary artery disease in Africans, Asians, and Caucasians? Are there differences in surgical outcomes across these populations?

In Africans and Asians, coronary artery disease is largely driven by genetic predisposition. In Caucasians, the predominant driver is sedentary lifestyle combined with diet — high-fat foods, alcohol, physical inactivity — which more than compensates for their lesser genetic predisposition. Surgical outcomes are comparable worldwide, with success rates upward of 90% and combined morbidity and mortality after CABG around 5 to 7% regardless of country. But the numbers in Asia and Africa are hugely underrepresented — if one million cardiac deaths annually in sub-Saharan Africa is the current reported figure, the true number with adequate diagnostic infrastructure would likely be closer to three million.

Regarding the 2-3-4-5 plant-based diet pyramid — India has a large vegetarian population that nominally follows this diet, yet cardiac events have increased significantly over the last two to three decades. How do you explain that?

The traditional Indian vegetarian population was genuinely following something close to this diet. What changed was cooking oil. Industrial cooking oils were repackaged and marketed under omega fatty acid branding — omega-3, then omega-6, now omega-9 — persuading consumers to abandon traditional cooking fats like mustard oil and olive oil for artificially processed, packaged products whose health claims aren't supported by meaningful clinical evidence. If the population simply returned to traditional cooking oils, it would likely cut the cardiac disease burden significantly. The pyramid isn't the problem; the oil in the pan is.

Very fit people and even elite athletes are having sudden cardiac events. Does physical fitness guarantee cardiac health?

No, it does not. Gyms typically require only a basic medical certificate, not triglyceride, homocysteine or CRP levels. The supplement industry is enormous, largely unregulated and mostly not FDA-approved. And building muscle mass ignores that the heart is also a muscle — when it hypertrophies beyond physiological bounds, that's called hypertrophic cardiomyopathy, not fitness. The footballer Christian Eriksen is instructive: he had a cardiac event at Euro 2020, received an ICD, returned to professional football, and years later the ICD detected and treated an arrhythmic episode with a single defibrillation — he felt dizzy, walked off, and was alive. Shane Warne's death, by contrast, fit the classic pattern: lifelong smoking, crash diets, and heavy alcohol.

Can LVADs replace heart transplantation altogether? What is the future of this space?

For patients above 55, LVADs have to a reasonable extent already replaced transplantation as destination therapy — they can run fifteen years without complications on antiplatelet and anticoagulant therapy alone, with no immunosuppression needed. Three developments will transform deceased-donor transplant over the next decade: donation after circulatory death, which could roughly double the donor pool; ex vivo machine perfusion devices like the TransMedics Organ Care System, which keep a donor heart beating outside the body for twelve to twenty-four hours or more, making cross-continental transport feasible; and xenotransplantation, with genetically modified pig hearts already transplanted into two human recipients. It's unlikely any engineered device will fully replicate a natural heart, though — transplantation will stay relevant for at least the next fifteen to twenty-five years.

What is the best approach to managing peripheral oedema — swelling of the feet — in a patient with HIV, pulmonary tuberculosis, and hypotension?

The first step is an urgent echocardiogram to establish ejection fraction precisely using Simpson's biplane method — the clinical picture at 35% and at 20% are entirely different territories. Below 20%, options are very limited; diuretics alone won't fully resolve the oedema. The Aquadex SmartFlow ultrafiltration system, with a 15ml prime volume removing 60 to 100ml of fluid per hour, is the logical next step when diuretics are failing. But with ejection fraction below 20% in the context of HIV and TB, and hypotension further constraining options, the situation is close to endgame — peritoneal dialysis is theoretically possible, but introducing a device into the body cavity of a patient with active communicable disease carries an infection risk that makes it unsafe in most circumstances.

Why can't a single specialist manage heart failure alone?

Because no single discipline, cardiologist, cardiac surgeon, physician, or intensivist, has the full picture; effective management requires a team debating the best path for each patient.

How many specialties make up a functioning heart team?

A minimum of six: cardiologist, cardiothoracic surgeon, respiratory physician, intensivist, general physician, and a preventive or family medicine specialist.

Does the same heart disease get treated the same way regardless of a patient's age?

No. The same disease might call for an open-chest total arterial coronary bypass at 43, a different approach entirely at 73, and simply optimised medical therapy focused on quality of life at 83.

What is the point of disagreement within a heart team?

Arguing through differing views is part of the process; it is how the team differentiates the right approach for a specific patient rather than applying one default treatment.

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