Consultant - Heart & Lung Transplant and Vascular Surgery, Artemis Hospitals, Gurgaon
Part 11 of 14 in All About Heart Failure & Coronary Artery Disease in African Population: The Way Forward
Total Arterial CABG: Why Graft Quality Matters More Than Technique
June 28, 2026
The pinnacle of coronary artery disease treatment, Dr. Purkayastha says, is CABG using bilateral internal mammary arteries (both the left and right internal mammary arteries used as conduits). A study comparing multi-arterial graft CABG with PCI across roughly 850 patients per arm found 13% mortality in the CABG group against 26% in the stenting group at one year, and 28% adverse events against 60%, published in the Annals of Thoracic Surgery.
On technique, his position is unambiguous: the quality of the graft matters more than the method used to deploy it. A LIMA-only robotic CABG is inferior to a total arterial open CABG. Whether the approach is minimally invasive, robotic or traditional open surgery is a clinical decision for the surgeon to make (not a request from the patient), and the goal has to stay the best quality of conduit, not the most fashionable technique.
This guide is based on a live Jivo Masterclass — Dr. Biswarup Purkayastha taught doctors across Africa on June 28, 2026.
FROM THE LIVE Q&A
Dr. Quet, DRC
What is the role of traditional alcohol in cardiomyopathy?
Dr. Biswarup Purkayastha
The evidence is unambiguous: any form of alcohol predisposes to cardiac dysfunction. Traditional drinks have been examined alongside commercially available alcohol in studies, and the myth that red wine protects the heart has been comprehensively debunked. Chronic alcohol consumption damages the heart, full stop. Whether someone chooses to drink socially is a personal decision, but scientifically there is no basis for recommending any alcohol for cardiac health.
Book a Consultation with Dr. Biswarup Purkayastha
Book on WhatsAppOr message us on WhatsApp: +91 98182 98669
Frequently Asked Questions
How do you manage the bleeding risk when loading a patient with 600mg aspirin and clopidogrel?▼
You do not manage it — you accept it, because that is your best option to open the coronary artery blockage. The bleeding risk is only a problem in a living patient. If the patient dies from a myocardial infarction for lack of intervention, there is no bleeding to manage.
What is the primary indication for using sacubitril/valsartan, and how is it dosed?▼
It should be started at the lowest possible dose — half a tablet, 25mg once daily, titrated over a week to 50mg, then 100mg, not typically exceeding 100mg once daily or 50mg twice daily. The primary indication is ejection fraction below 45% with elevated NT-proBNP. In a patient with ejection fraction below 35% and high NT-proBNP, it should be initiated at the lowest dose and titrated carefully upward.
From your experience, what is the relative epidemiology of coronary artery disease in Africans, Asians, and Caucasians? Are there differences in surgical outcomes across these populations?▼
In Africans and Asians, coronary artery disease is largely driven by genetic predisposition. In Caucasians, the predominant driver is sedentary lifestyle combined with diet — high-fat foods, alcohol, physical inactivity — which more than compensates for their lesser genetic predisposition. Surgical outcomes are comparable worldwide, with success rates upward of 90% and combined morbidity and mortality after CABG around 5 to 7% regardless of country. But the numbers in Asia and Africa are hugely underrepresented — if one million cardiac deaths annually in sub-Saharan Africa is the current reported figure, the true number with adequate diagnostic infrastructure would likely be closer to three million.
Regarding the 2-3-4-5 plant-based diet pyramid — India has a large vegetarian population that nominally follows this diet, yet cardiac events have increased significantly over the last two to three decades. How do you explain that?▼
The traditional Indian vegetarian population was genuinely following something close to this diet. What changed was cooking oil. Industrial cooking oils were repackaged and marketed under omega fatty acid branding — omega-3, then omega-6, now omega-9 — persuading consumers to abandon traditional cooking fats like mustard oil and olive oil for artificially processed, packaged products whose health claims aren't supported by meaningful clinical evidence. If the population simply returned to traditional cooking oils, it would likely cut the cardiac disease burden significantly. The pyramid isn't the problem; the oil in the pan is.
Very fit people and even elite athletes are having sudden cardiac events. Does physical fitness guarantee cardiac health?▼
No, it does not. Gyms typically require only a basic medical certificate, not triglyceride, homocysteine or CRP levels. The supplement industry is enormous, largely unregulated and mostly not FDA-approved. And building muscle mass ignores that the heart is also a muscle — when it hypertrophies beyond physiological bounds, that's called hypertrophic cardiomyopathy, not fitness. The footballer Christian Eriksen is instructive: he had a cardiac event at Euro 2020, received an ICD, returned to professional football, and years later the ICD detected and treated an arrhythmic episode with a single defibrillation — he felt dizzy, walked off, and was alive. Shane Warne's death, by contrast, fit the classic pattern: lifelong smoking, crash diets, and heavy alcohol.
What is considered the gold standard technique for CABG?▼
Using bilateral internal mammary arteries, both the left and right, as conduits.
What did the study comparing multi-arterial graft CABG with PCI find?▼
Across roughly 850 patients per arm, 13% mortality in the CABG group against 26% in the stenting group at one year, and 28% adverse events against 60%, published in the Annals of Thoracic Surgery.
Is a robotic CABG always better than an open one?▼
Not necessarily; a LIMA-only robotic CABG is inferior to a total arterial open CABG, because graft quality matters more than the method used to deploy it.
Who should decide whether a CABG is performed as minimally invasive, robotic, or open surgery?▼
The surgeon, based on achieving the best quality of conduit, not the patient's preference for a particular technique.
In This Series: All About Heart Failure & Coronary Artery Disease in African Population: The Way Forward
- 1.Heart Failure and Coronary Artery Disease in the African Population
- 2.Why Heart Failure Looks Different in Africa: Earlier Onset, Later Diagnosis
- 3.What's Actually Causing Heart Failure in Africa: Hypertension, Rheumatic Disease, HIV and TB
- 4.The Heart Team: Why No Single Specialist Should Manage Heart Failure Alone
- 5.Modern Heart Failure Drugs: SGLT2 Inhibitors, ARNIs, and Beyond Digoxin
- 6.Surgical Options for Heart Failure: From Balloon Valvotomy to Heart Transplant
- 7.LVADs and the Future of Heart Transplantation
- 8.Recognising a Heart Attack: Why Symptoms Differ in Women and Diabetics
- 9.Treating a Heart Attack Without Immediate Access to a Cath Lab
- 10.PCI vs CABG: What the Evidence Actually Shows
- 11.Total Arterial CABG: Why Graft Quality Matters More Than Technique
- 12.Preventing Coronary Artery Disease: Diet, the Oil Myth, and the Limits of Fitness
- 13.Tricuspid and Mitral Valve Repair vs Replacement: A Surgeon's Real-World Approach
- 14.Managing Refractory Heart Failure With HIV and Tuberculosis