Senior Consultant & Unit Head, Interventional Cardiology, BLK-Max Super Speciality Hospital, New Delhi
Part 4 of 8 in Diagnosis and Management of Acute Coronary Artery Disease
Managing a Heart Attack: STEMI vs NSTEMI Protocols
June 2, 2024
STEMI and NSTEMI are managed on very different timelines, and understanding why explains why speed matters so much for one and not the other.
STEMI: treat immediately, don't wait for tests
For STEMI, a single ECG is enough to act on. The patient is given IV opioids for pain, sorbitrate (nitrate) to relieve pain, and oxygen, and the artery is opened immediately: PCI (stenting) is the gold standard, and if PCI isn't available, thrombolytic (clot-busting) therapy is given instead. Emergency bypass surgery is needed only rarely.
NSTEMI and unstable angina: stabilise, then decide on timing
For NSTEMI and unstable angina, the artery is not assumed to be 100% blocked, so patients are started on antiplatelet medication and taken for angiography after stabilisation. Patients who continue to have pain or are deteriorating go for early angiography, generally within the first two days; otherwise, lower-risk patients are managed on antiplatelets for two days before angiography. Taking every patient directly to the cath lab is not necessarily more beneficial than this staged approach.
This article is based on a Jivo Masterclass session conducted by Dr. Vikas Thakran, Senior Consultant & Unit Head, Interventional Cardiology, BLK-Max Super Speciality Hospital, New Delhi. The article has been summarised with the assistance of an AI tool from the original masterclass recording. Watch the full Masterclass recording
Looking for a cardiology or heart attack consultation? Get in touch with the Jivo team
This guide is based on a live Jivo Masterclass: Dr. Vikas Thakran taught doctors across Africa on June 2, 2024.
FROM THE LIVE Q&A
General Dimma
At what stage do we administer nitrates in managing ACS, what is the best source, and what are the nutritional considerations in ACS management?
Dr. Vikas Thakran
Sublingual nitrate (sorbitrate) is the treatment of choice since it acts quickly and is widely available, except in patients with inferior wall STEMI, where nitrates should be used cautiously. If sublingual nitrate doesn't relieve pain, intravenous nitroglycerin can be given alongside opioids for severe pain. On nutrition, the acute-phase approach is largely about hydration status: patients presenting late with severe breathlessness should be given a low-salt diet and IV fluids should be limited to avoid overhydration. For long-term management after an ACS event, high-fat and deep-fried foods should be avoided to keep cholesterol levels down.
Book a Consultation with Dr. Vikas Thakran
Book on WhatsAppOr message us on WhatsApp: +91 98182 98669
Frequently Asked Questions
What are the main causes of acute coronary syndrome?▼
Smoking in young patients, diabetes, hypertension, a family history of cardiac disease, a sedentary lifestyle, and lack of sleep are the major risk factors. Pollution and extremes of temperature can also precipitate an event.
What is the role of cardiac defibrillation?▼
During an acute coronary event, external defibrillation is used for life-threatening ventricular tachycardia or ventricular fibrillation, whether at presentation, during the procedure, or post-operatively. On longer-term follow-up, patients with poor heart function (a low ejection fraction) may need an ICD, a device similar to a pacemaker, implanted to protect against these arrhythmias.
What are the expected complications of an angioplasty procedure?▼
Angioplasty is roughly 95 to 98% safe. The complications that can occur are access-site bleeding from the hand or groin, and rarer complications related to the coronary arteries themselves, such as stent thrombosis (a blocked stent) or, in difficult vessels, a perforation.
What motivates this line of work?▼
A heart attack patient left untreated has a 30 to 50% chance of dying; treated promptly with a procedure or thrombolysis, that risk falls to around 5%. Saving the largest number of lives in the smallest amount of time, across the globe, is the reason and the motivation.
For a patient with anterior wall MI who has also fainted and is in a critical condition, how do you manage evacuation to an Indian hospital?▼
Jivo's international team manages the entire process end to end, from the visa process to ambulance transfer at the airport, and makes sure family members travelling with the patient are comfortable too. They first take the patient's details and advise on the right course of action, so the point of contact should be the international team, who will coordinate directly with BLK-Max.
How is STEMI managed?▼
Immediately, based on ECG alone, without waiting for further tests: IV opioids, nitrates and oxygen, followed by PCI (stenting) as the gold standard, or thrombolytic therapy if PCI is not available.
How is NSTEMI managed differently from STEMI?▼
Patients are stabilised on antiplatelet medication first; those who continue to have pain or are deteriorating go for early angiography (within two days), while lower-risk patients are managed medically before angiography.
In This Series: Diagnosis and Management of Acute Coronary Artery Disease
- 1.Acute Coronary Syndrome
- 2.How a Heart Attack Develops: From Plaque to Complete Blockage
- 3.STEMI, NSTEMI and Unstable Angina: Reading the ECG
- 4.Managing a Heart Attack: STEMI vs NSTEMI Protocols
- 5.How PCI (Angioplasty) Is Performed, and When Bypass Is Better
- 6.Angioplasty: Complication Rates and Why Fast Treatment Matters
- 7.Heart Attack Risk Factors, Nitrate Therapy and Nutrition
- 8.Hospital Facilities and Evacuating Critical Patients Internationally