OncologyDr. Shubham JainCancer Warning Signs

Senior Director, Surgical Oncology, Fortis Hospital, Vasant Kunj, New Delhi

Series overview · 10 articles

When to Suspect Cancer and How to Refer

January 25, 2026

Cancer diagnosed at an advanced stage restricts a surgical oncologist's ability to offer a cure, and the gap between a patient's first symptom and their referral to a specialist is where much of the difference in outcome gets decided. This guide is based on a Jivo Masterclass by Dr. Shubham Jain, Senior Director of Surgical Oncology at Fortis Hospital, Vasant Kunj, New Delhi, and introduces a series on the warning signs and screening pathways for the cancers he treats most often.

A role built on early recognition, not just surgery

Dr. Jain frames the primary healthcare provider’s role around three things: recognising cancer early by knowing its symptoms, following up promptly on persistent or unusual findings, and pushing screening for the cancers most common in the doctor’s own population. He notes that in Africa, prostate cancer in men and breast cancer in women are the two he sees most often, and that both can be identified early with a major impact on survival.

Seven warning signs that should prompt suspicion

Across the masterclass, Dr. Jain sets out seven warning signs: a gradually increasing, usually painless swelling or lump; a persistent unexplained sore or changing skin lesion that will not heal; persistent hoarseness or a nagging cough, especially with blood-streaked sputum or a tobacco history; persistent bloating or abdominal symptoms, sometimes with jaundice; any unscheduled or unexplained bleeding or discharge; a recent change in dietary, bowel or bladder habits or breathing difficulty; and any recent, otherwise unexplained pain, recurrent infection or functional decline.

What this series covers

This series works through each of these warning signs in turn, from breast lumps and triple assessment to hoarseness and voice rehabilitation after laryngectomy, persistent cough and low-dose CT screening, abdominal bloating and ovarian cancer, abnormal bleeding and cervical cancer prevention, and changes in bowel habit and colorectal cancer screening. It closes with the myths that keep patients from timely treatment and how a cancer of unknown primary is worked up when the source is not obvious.

This article is based on a Jivo Masterclass session conducted by Dr. Shubham Jain, Senior Director, Surgical Oncology, Fortis Hospital, Vasant Kunj, New Delhi. The article has been summarised with the assistance of an AI tool from the original masterclass recording. Watch the full Masterclass recording

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This guide is based on a live Jivo Masterclass — Dr. Shubham Jain taught doctors across Africa on January 25, 2026.

Watch the full recording, or read the guide above.

FROM THE LIVE Q&A

HO

Host (Varun, Jivo Healthcare)

How should a doctor practising in a resource-constrained setting, without enough diagnostic facilities to screen large populations, know which symptoms genuinely warrant referral and which could be a false alarm?

SJ

Dr. Shubham Jain

Any suspected cancer requires resources for investigation and treatment, so it should be evaluated at a good high-volume centre that gives the best chance of cure. It is difficult to assess the outcome or treatment at an initial stage, so the primary reliance has to be on the clinical signs and symptoms already discussed, which are the basis for suggesting a patient be evaluated at a high-volume centre.

See all 12 questions from this masterclass →

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Frequently Asked Questions

Can you tell us something about malignant wounds?

A malignant wound anywhere needs to be confirmed on biopsy to establish the exact reason for it, and it should not be expected to heal on its own. It should be subjected to a biopsy to confirm the nature of the malignancy and the treatment options, with appropriate imaging to understand the underlying structures involved, and surgery offered if the wound is resectable.

A patient had laryngeal cancer and surgery affected his voice box. He wants an aid to help him use his voice but does not want an invasive procedure. Are there any options available for him?

Yes, definitely. An electrolarynx is an external prosthesis: once the device is attached to the skin it creates vibrations at high speed and the patient can vocalise using it.

What are the latest screening tests available for early detection of different cancers?

Tumour markers can be used, but it is important to understand the patient's age, family history and smoking status first. At a basic level, a mammography for women, an ultrasound of the whole abdomen for endometrial or ovarian cancer, a serum PSA blood test for men with suspected prostate cancer, and a CT scan of the chest for smokers can be recommended. The frequency varies: colon cancer screening can be a colonoscopy every ten years, or a sigmoidoscopy with a faecal occult blood test.

Biopsy is often the best way to detect cancer, but it usually takes a long time. Are there any faster options or alternatives?

This is a real issue even in India, where processing time for biopsies can be high in some regions. One workaround is relying more on FNAC, which is not the best strategy but can guide treatment decisions in select situations where a diagnosis is otherwise delayed. A second option is a frozen section facility, which gives some confirmation quickly but is resource-intensive and usually only available at high-volume cancer centres. Short of that, it is best to refer to an oncologist who can guide where a biopsy should be taken from for the best results.

What are the myths in assessing suspected cancer patients?

The most important myth is patients' hesitancy to get a biopsy done, fearing it will cause the cancer to spread. A biopsy is one of the most crucial tests a cancer patient needs, and if planned and performed correctly it will not cause the cancer to spread. Another myth is that patients believe cancer is their own fault, from dietary habits or indulgences like tobacco or alcohol. More cases are now understood to happen because of environment or genetics rather than a patient's own fault, and it is important to destigmatise patients suffering from cancer, since stigma is what keeps them from seeking timely treatment.

What are the seven warning signs of cancer according to this masterclass?

A gradually increasing, usually painless lump or swelling; a persistent unexplained sore or worsening skin lesion; persistent hoarseness or a nagging cough, especially with blood-streaked sputum or a tobacco history; persistent bloating or abdominal symptoms, sometimes with jaundice; unscheduled or unexplained bleeding or discharge; a recent change in bowel, bladder or dietary habits or breathing difficulty; and any recent, otherwise unexplained pain, recurrent infection or functional decline.

Which cancers does Dr. Shubham Jain see most often in African patients?

He notes that prostate cancer in men and breast cancer in women are the cancers he sees most commonly among African patients, both of which can be identified early with a major impact on survival.

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