Benign Growth in Uterus Causing Gynaecological Problems

Senior Director & Unit Head - Obstetrics And Gynaecology, Robotic Surgery, Gynaecologic Laparoscopy, Pregnancy Management
Max Hospital, Gurgaon
August 25, 2024
Dr. Suman Lal, Principal Director & Unit Head, Obstetrics and Gynaecology at Max Hospital, Gurugram, walks through uterine fibroid risk factors, diagnosis and classification, medical and surgical management, and their impact on fertility and pregnancy. The extensive discussion covers embolization, myomectomy techniques, PCOS, endometriosis, and preventing post-surgical adhesions.
Questions Doctors Asked Dr. Suman Lal
Real questions from the live masterclass, answered by Dr. Suman Lal, Senior Director & Unit Head - Obstetrics And Gynaecology, Robotic Surgery, Gynaecologic Laparoscopy, Pregnancy Management.
Can you talk about the link between folic acid intake and uterine fibroids?
Asked by Moderator
Any diet rich in folic acid gives nutritional support to the uterus and can help reduce fibroid growth in epidemiological studies, but folic acid isn't a treatment. It can be given as a preventive measure in high-risk cases, not as a cure once a fibroid is present.
Answered by Dr. Suman Lal
What are some of the symptoms of a high-risk pregnancy if it can be detected only with the fibroid?
Asked by Moderator
Pelvic pain out of proportion to a normal pregnancy, urinary symptoms from an anterior fibroid pressing on the bladder, rectal or pelvic pressure from a posterior fibroid, and localised pain when the uterus is touched, which often signals degeneration within the fibroid. Any of these should prompt an ultrasound.
Answered by Dr. Suman Lal
How exactly do fibroids cause throbbing and burning pain during urination, and does it predispose patients to UTIs?
Asked by Jivo Doctor Partner (name unclear from transcript)
Since the bladder sits anterior to the uterus, a fibroid growing on the front surface of the uterus can press into and separate the bladder, causing difficulty passing urine and the resulting pain sensation.
Answered by Dr. Suman Lal
Can tranexamic acid be used in treatment, like reducing the size of a myoma?
Asked by Moderator
No. Tranexamic acid doesn't reduce the size of a fibroid. It works by promoting clot formation, so it reduces heavy bleeding caused by a fibroid, but has no effect on the fibroid's size.
Answered by Dr. Suman Lal
How far can progesterone hormone reduce the size of a fibroid?
Asked by Moderator
Progesterone reduces fibroid size by only around 20%. It's given to women waiting for surgery or unable to have surgery who have heavy bleeding, not routinely to patients without symptoms.
Answered by Dr. Suman Lal
What is the management of fibroids using medication without surgery, and what are the possibilities?
Asked by Moderator
If bleeding is heavy and the fibroid isn't inside the cavity, medical management with painkillers, oral contraceptive pills, and GnRH agonist injections is possible. GnRH injections reduce fibroid size but the effect reverses within six months to a year of stopping, so medical management is generally a one-to-two year bridge, not a permanent solution, and is most useful pre-menopause, pre-surgery, or pre-pregnancy attempts.
Answered by Dr. Suman Lal
What is the role of the gonadotropin agonists used in India, Lupron and Goserelin?
Asked by Moderator
Both are effective at reducing fibroid size, by around 40-50%. Different centres use different ones, but either can be used.
Answered by Dr. Suman Lal
Do you suggest that a scan measuring a 5cm fibroid should be surgically removed?
Asked by Moderator
Not automatically. If the 5cm fibroid is inside the uterus causing heavy bleeding or obstruction, yes. If it's outside the uterus and not causing any problem, there's no need to operate. If it's in the muscle layer and the patient is trying to conceive or undergo IVF, removal is often needed. Symptoms, location and fertility goals all have to be weighed together, not size alone.
Answered by Dr. Suman Lal
What is the relationship between fibroids and menstrual pain?
Asked by Moderator
A fibroid inside the uterine cavity acts like a foreign body. When menstrual contractions begin, the uterus tries to expel the fibroid the same way labour contractions try to expel a baby, causing cramping. An intramural fibroid also increases the uterus's surface area, independently increasing both pain and bleeding.
Answered by Dr. Suman Lal
What is the fate of myoma nuclei after embolization, and why is it contraindicated in women wishing to conceive in the future?
Asked by Moderator
Embolization blocks the artery supplying the uterus, so blood flow to the entire uterus decreases, not just to the fibroid. That reduced blood flow is exactly why the procedure is contraindicated for women planning pregnancy afterward, since it can compromise the nutrition and growth of a future baby. For these patients, myomectomy (surgical removal) is the right choice instead.
Answered by Dr. Suman Lal
In cases of infertility, is there any actual management in terms of medication?
Asked by Moderator
Infertility has several possible causes, blocked tubes, inadequate egg count, or structural issues like fibroids, adenomyosis or endometriosis, and each needs a different treatment. For a woman with fibroids who wants to avoid surgery before conceiving, a GnRH agonist can shrink the fibroid over six to nine months, after which medication can be given to support pregnancy.
Answered by Dr. Suman Lal
Can endometriosis be cured completely, and how can someone with endometriosis get pregnant easily?
Asked by Moderator
Complete cure of endometriosis is mostly not possible, but early detection and adequate treatment are key. If an endometrioma is found, a thorough cystectomy removing all endometriotic tissue at the first surgery is the most important step; getting this first surgery right substantially reduces recurrence and preserves the chance of pregnancy.
Answered by Dr. Suman Lal
What is the best way to treat PCOS?
Asked by Moderator
PCOS is fundamentally a lifestyle disease, so lifestyle changes, decreased stress, better diet, exercise and meditation, are the most important treatment. Beyond that, treatment targets specific symptoms: hormonal pills for delayed periods, targeted medication for acne or hair loss, and ovulation induction with specialist support for women not conceiving.
Answered by Dr. Suman Lal
After a myomectomy there is some adhesion trouble. Is physical therapy the only helpful therapy for reducing those adhesions?
Asked by Moderator
No. Adhesion formation is a normal surgical risk that varies between patients regardless of physical therapy, medication or diet. What genuinely helps is surgical technique: precisely opposing tissue, avoiding pooled blood inside the abdomen, thorough cleaning of the surgical field, placing a drain when there's more bleeding, and using an anti-adhesive barrier such as omentum or a purpose-made material over the repair site. Proper instrument sterilisation also matters directly, since infection significantly increases adhesion formation.
Answered by Dr. Suman Lal
What is the real cause of fibroids?
Asked by Moderator
It's still not fully known after many years of study. The working theory is that unopposed oestrogen in the body, when the uterus isn't balanced by adequate progesterone, promotes fibroid formation, but the exact mechanism remains unclear.
Answered by Dr. Suman Lal
Read the Full Article Series
- 1.Uterine Fibroids: A Complete Guide by Dr. Suman Lal
- 2.What Are Uterine Fibroids? Risk Factors and Symptoms
- 3.Diagnosing and Classifying Fibroids by Location
- 4.Fibroids, Fertility, Pregnancy Risk and Menstrual Pain
- 5.Medical Management: Painkillers, Progesterone and GnRH Agonists
- 6.Uterine Artery Embolization: When It Works and When It's Contraindicated
- 7.Surgical Removal: Hysteroscopic, Laparoscopic and Robotic Myomectomy
- 8.Beyond Fibroids: PCOS, Endometriosis and Infertility
- 9.Preventing Adhesions After Myomectomy: What Actually Works