OrthopaedicsDr. Ramkinkar JhaJoint Replacement

Director, Department of Orthopaedics, CK Birla Hospital, Gurugram, India

Part 9 of 18 in Hip Replacement, Knee Replacement, Revision Surgery & Arthroscopies

Managing Infection After Joint Replacement

August 7, 2026

Infection after joint replacement surgery is treated aggressively from the outset, with acute infections managed through surgical debridement rather than antibiotics alone, while long-standing infections require a staged revision procedure.

How Is Acute Infection After Joint Replacement Treated?

Dr. Ramkinkar Jha is clear that antibiotics alone will not suffice for an acute infection following joint replacement: the joint must be surgically cleaned, sometimes through multiple debridements, until it is confirmed clear from the inside. In the knee, the polyethylene component may also be exchanged, a drain placed for three to five days, and antibiotics given as an adjuvant to surgery rather than as the primary treatment.

How Is Long-Standing Infection Managed?

When infection has been present for more than a month, a staged revision is usually required. In the first stage, the implant is removed and an antibiotic spacer is placed, followed by six weeks of monitoring using infection markers such as ESR, CRP and full blood count until these return to normal and the skin has healed. Only then does the patient proceed to the second stage, a revision total joint replacement.

Are There Other Infection Risks Around Orthopaedic Implants?

External fixators, sometimes used temporarily around fractures before or instead of joint replacement, carry their own risk of pin tract infection at the point where the fixator pins pass through the skin, which can progress to osteomyelitis if not treated. Recognising and treating infection early, whether around an external fixator or a joint replacement, is essential to protecting the long-term success of joint replacement surgery.

← Hip Resurfacing for Young and Active Patients | Series index | Implant Safety: MRI Compatibility, Follow-Up and Durability →

This article is based on a Jivo Masterclass session conducted by Dr. Ramkinkar Jha, Chief and Unit Head, Orthopaedics, Artemis Hospitals, Gurgaon, India. The article has been summarised with the assistance of an AI tool from the original masterclass recording. Watch the full Masterclass recording

This guide is based on a live Jivo Masterclass — Dr. Ramkinkar Jha taught doctors across Africa on July 14, 2024.

FROM THE LIVE Q&A

DR

Dr. Atanda Solomon

How effective is medical therapy, and what is the role of steroids in early-stage osteoarthritis?

RJ

Dr. Ramkinkar Jha

Medical therapy is the first line of treatment — it should be tried first, and once pain is not relieved with medical therapy and physical therapy, and the patient is having difficulty in activities of daily living, then the patient becomes a candidate for surgery.

See all 7 questions from this masterclass →

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Frequently Asked Questions

What is the success rate of replacement therapy in terms of biocompatibility and durability?

The survivorship of newer implants, taking an average value, is more than 20 to 25 years, though there's a range. To measure success there's a prerequisite: we presume the patient has taken care of the joint, followed the precautions, physical therapies and exercises they've been told — the value I've mentioned is the average assuming that's been taken care of.

How often is the implant reviewed, and will it need to be removed, or is it permanent?

It's a permanent, non-removable procedure — it doesn't need to be removed. The follow-ups: the first milestone is at two weeks, to remove the stitches, then six weeks post-surgery, then three months, six months, and then annually.

What special care must an athlete take after a hip replacement?

In athletes the demand of activity is much more than the normal population — jumping, contact sports — and there's wear and tear involved in the artificial joint over time. We generally tell patients not to jump or run, for the sake of the longevity of the implant — the more activity, the more wear, and the more chance of needing revision surgery. First we tell them to change their activity level if possible; if that's not possible, there are certain implant variations available, like hip resurfacing or metal-on-metal implants, which can be offered if it's mandatory for the athlete to continue their sport — though ceramic implants are not good for them because of a higher chance of breakage.

If a patient develops an infection around the implant, should the implant be removed or treated with antibiotics? And are there implants that are MRI-compatible?

For infection: understand the kind and duration of it. If it's acute, be very aggressive — antibiotics alone won't suffice, don't hesitate to go inside and clean the joint, with multiple debridements till it feels clean; antibiotics work as an adjuvant, not the primary therapy. In the knee you can also change the polyethylene component, put a drain for three to five days, give antibiotics. But if it's longstanding — more than a month — you may need staged revision surgery: stage one, remove the implant and put an antibiotic spacer, monitor for six weeks until infection markers are normal and skin has healed, then stage two, the revision total replacement. On MRI: all joint replacements can have an MRI done, provided the implant is well fixed — if it's unstable, MRI may not be a good idea, but if the joint is stable, MRI can be done using implant-specific coils that neutralise the implant artefact.

Can you explain the '90 degree rule' for hip replacement surgery?

This is a common perception, actually — in the first six to eight weeks we don't want the patient to bend beyond 90 degrees, talking about hip replacements, to reduce the chances of dislocation so the capsule heals well. That's the 90 degree rule for hip replacement.

How is an acute infection around a joint replacement treated?

Antibiotics alone are not sufficient. The joint must be surgically cleaned, sometimes through multiple debridements; in the knee the polyethylene component may also be exchanged, a drain placed for three to five days, and antibiotics given as an adjuvant to surgery.

What happens when an infection around a joint replacement has been present for more than a month?

A staged revision is usually required. The first stage removes the implant and places an antibiotic spacer, followed by six weeks of monitoring with infection markers until they return to normal and the skin has healed, before the second stage, a revision total joint replacement.

Can an external fixator used to treat a fracture cause infection?

Yes, external fixators carry a risk of pin tract infection where the pins pass through the skin, which can progress to osteomyelitis if not treated.

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