Pain Medicine & Palliative CareDr. Ashu Kumar JainChronic Pain Management

Chief, Pain Medicine & Palliative Care, Artemis Hospitals, Gurgaon, India

Part 8 of 13 in Advances in Chronic Pain Treatment: The Latest Trends

Sciatica and Failed Back Surgery: Transforaminal Epidural Adhesiolysis

July 12, 2026

For sciatica caused by scar tissue and adhesions around a nerve root, Dr. Jain performs transforaminal epidural adhesiolysis: irrigating the anterior epidural space with saline and hyaluronidase to release adhesions at the L3 to S1 levels, using only a minimal 2mg dose of dexamethasone per level rather than the larger steroid doses this procedure has historically relied on.

The same approach treats failed back surgery syndrome: a transforaminal epidural below the level of a previous fixation releases a nerve root trapped in post-surgical scar tissue, while RFA of the facet joints above the fixation addresses the adjacent-segment pain that often develops afterward, in patients who continue to have pain after spine surgery, treated in the cathlab rather than through a second operation.

This guide is based on a live Jivo Masterclass — Dr. Ashu Kumar Jain taught doctors across Africa on July 12, 2026.

FROM THE LIVE Q&A

DR

Dr. Ivan, Uganda

In RFA, can the treated nerves regenerate? And if so, when can pain reoccur?

AK

Dr. Ashu Kumar Jain

The nerve cannot truly regenerate in the clinical sense. When there is nerve injury, the patient can go into complex regional pain syndrome Type II. Nerve regeneration takes a very long time and the results are poor — if you believe you can treat a patient through nerve regeneration, in present-day practice that is a myth.

See all 7 questions from this masterclass →

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Frequently Asked Questions

Which local anaesthetics, steroids and adjuvants do you usually use for different nerve blocks?

For nerve blocks we use ropivacaine. For steroids, we primarily use dexamethasone in spinal procedures. For joint injections, we usually use Kenacort (triamcinolone).

Is there a list of drugs under your remit that are specialist-prescription only, and how do you manage supply — we have supply problems for certain drugs in Zambia.

In India, opioids are scheduled drugs — you need a prescription from a competent doctor: a pain specialist, anaesthesiologist or neurologist, not a general surgeon or ENT. For morphine and fentanyl specifically, the hospital needs a government licence to hold a certain quantity, and we use a special designated government form that we stamp, with patients required to bring a consumption chart we submit to the drug controller. Tramadol, tapentadol and buprenorphine don't need special licensing, but you do need a valid prescription from a competent doctor.

What are the most common misconceptions community doctors have about facet joint injection?

The first issue is simply diagnosis — ninety per cent of doctors not trained for this kind of spinal pain can't diagnose facetogenic pain. We call it axial pain, which includes facetogenic and discogenic pain, and gabapentinoids are of no use for it whatsoever — yet eight out of ten patients with axial pain are given these drugs with no results. It's a diagnostic challenge first: specific questions in the history, a specific examination, then a diagnostic block to confirm the pain is coming from the facet before proceeding to facet joint RFA.

Bone marrow transplant is a cure for sickle cell disease but isn't offered to every patient, including for cost reasons. How can sickle cell patients with chronic pain from avascular necrosis of the femoral head benefit?

If the femoral head is involved, we can perform radiofrequency ablation of the hip joint, ablating the articular nerves supplying the joint — it's a very rewarding procedure. But if the pain is arising from the bone itself or visceral involvement, the best approach is opioid analgesics rather than high-dose NSAIDs, which will damage the kidneys. Primary management is opioid-based — morphine or tramadol with paracetamol and a neuropathic agent — and where there is a specific anatomical target, we address that interventionally as well.

Quite often a patient presents in pain and there's a surgical solution, and sometimes it falls in your domain where surgery isn't required. How do physicians decide when a patient should go for surgery versus pain management?

According to international Spine Society guidelines, any pain coming from the spine where the primary problem is pain alone does not require surgery. The indications for surgery are disability — foot drop, motor or sensory deficit — or more than moderate to severe canal stenosis on MRI, where pain intervention can buy time but can't treat the disease. If a patient comes to me with a neurological deficit, I immediately refer to the spine surgeon and don't proceed with intervention. If pain is the only presenting symptom, we treat it — there's a very clear demarcation.

What causes sciatica from scar tissue, and how is it treated without surgery?

Scar tissue and adhesions can form around a nerve root and cause sciatica. Transforaminal epidural adhesiolysis treats this by irrigating the anterior epidural space with saline and hyaluronidase to release the adhesions, typically at the L3 to S1 levels.

How much steroid is used in adhesiolysis for sciatica today?

Only a minimal 2mg dose of dexamethasone per level is used, a marked reduction from the larger steroid doses this procedure has historically relied on.

Can pain after spine surgery be treated without a second operation?

Yes. Failed back surgery syndrome can be addressed with a transforaminal epidural below the level of the previous fixation to release a nerve root trapped in scar tissue, performed in the cathlab rather than through a second operation.

What causes new pain to develop next to a previous spinal fixation?

Adjacent-segment facetogenic pain often develops after fixation. It is addressed with radiofrequency ablation of the facet joints above the level of the fixation.

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