Chief, Pain Medicine & Palliative Care, Artemis Hospitals, Gurgaon, India
Part 2 of 13 in Advances in Chronic Pain Treatment: The Latest Trends
Trigeminal Neuralgia: Radiofrequency Ablation vs Surgery
July 12, 2026
Trigeminal neuralgia produces a sharp, shooting, electric-shock-like pain in one of the three divisions of the trigeminal nerve, severe enough that patients can't eat, speak, wash their face or sit under a fan. Eighty per cent of patients respond to medical management alone (carbamazepine, oxcarbazepine or eslicarbazepine), but for those who don't, Dr. Jain's first-line intervention is radiofrequency ablation (RFA) of the trigeminal ganglion: a day-care procedure taking about half an hour, with results above 95%.
A persistent misconception is that a neurovascular loop on MRI rules out RFA in favour of microvascular decompression (MVD), an open surgical procedure. Dr. Jain is explicit that this isn't supported by clinical evidence — he has treated many patients with a neurovascular loop using RFA alone, confirming electrode position first by stimulating the nerve and checking that the patient feels it in their usual pain distribution.
This guide is based on a live Jivo Masterclass — Dr. Ashu Kumar Jain taught doctors across Africa on July 12, 2026.
FROM THE LIVE Q&A
Dr. Chingis, Kazakhstan
Which local anaesthetics, steroids and adjuvants do you usually use for different nerve blocks?
Dr. Ashu Kumar Jain
For nerve blocks we use ropivacaine. For steroids, we primarily use dexamethasone in spinal procedures. For joint injections, we usually use Kenacort (triamcinolone).
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Frequently Asked Questions
Is there a list of drugs under your remit that are specialist-prescription only, and how do you manage supply — we have supply problems for certain drugs in Zambia.▼
In India, opioids are scheduled drugs — you need a prescription from a competent doctor: a pain specialist, anaesthesiologist or neurologist, not a general surgeon or ENT. For morphine and fentanyl specifically, the hospital needs a government licence to hold a certain quantity, and we use a special designated government form that we stamp, with patients required to bring a consumption chart we submit to the drug controller. Tramadol, tapentadol and buprenorphine don't need special licensing, but you do need a valid prescription from a competent doctor.
What are the most common misconceptions community doctors have about facet joint injection?▼
The first issue is simply diagnosis — ninety per cent of doctors not trained for this kind of spinal pain can't diagnose facetogenic pain. We call it axial pain, which includes facetogenic and discogenic pain, and gabapentinoids are of no use for it whatsoever — yet eight out of ten patients with axial pain are given these drugs with no results. It's a diagnostic challenge first: specific questions in the history, a specific examination, then a diagnostic block to confirm the pain is coming from the facet before proceeding to facet joint RFA.
Bone marrow transplant is a cure for sickle cell disease but isn't offered to every patient, including for cost reasons. How can sickle cell patients with chronic pain from avascular necrosis of the femoral head benefit?▼
If the femoral head is involved, we can perform radiofrequency ablation of the hip joint, ablating the articular nerves supplying the joint — it's a very rewarding procedure. But if the pain is arising from the bone itself or visceral involvement, the best approach is opioid analgesics rather than high-dose NSAIDs, which will damage the kidneys. Primary management is opioid-based — morphine or tramadol with paracetamol and a neuropathic agent — and where there is a specific anatomical target, we address that interventionally as well.
Quite often a patient presents in pain and there's a surgical solution, and sometimes it falls in your domain where surgery isn't required. How do physicians decide when a patient should go for surgery versus pain management?▼
According to international Spine Society guidelines, any pain coming from the spine where the primary problem is pain alone does not require surgery. The indications for surgery are disability — foot drop, motor or sensory deficit — or more than moderate to severe canal stenosis on MRI, where pain intervention can buy time but can't treat the disease. If a patient comes to me with a neurological deficit, I immediately refer to the spine surgeon and don't proceed with intervention. If pain is the only presenting symptom, we treat it — there's a very clear demarcation.
The concern with opioids for conditions like avascular necrosis is that they can be habit-forming or cause addiction — can you address that?▼
If you use opioids for chronic low back pain, knee pain or musculoskeletal pain, yes, they are habit-forming. But for cancer pain, and for pain like sickle cell disease — which we manage on the same lines as cancer pain — they are never habit-forming. Visceral pain is mediated by the sympathetic nervous system and doesn't respond to conventional NSAIDs, so it needs neuropathic agents and opioids in combination; back pain, knee pain and shoulder pain are peripheral musculoskeletal or neuropathic pain and don't carry the same opioid receptor expression, which is why the risk profile is so different between the two.
What are the classic symptoms of trigeminal neuralgia?▼
Sharp, shooting, electric-shock-like pain in one of the three divisions of the trigeminal nerve, severe enough that patients cannot eat, speak, wash their face, or sit under a fan.
Does trigeminal neuralgia always require surgery?▼
No. Eighty per cent of patients respond to medical management alone. For those who do not, radiofrequency ablation of the trigeminal ganglion is the first-line intervention, a day-care procedure taking about half an hour with results above 95%.
Does a neurovascular loop on MRI mean a patient needs microvascular decompression instead of radiofrequency ablation?▼
No. This is a persistent misconception. The claim that a neurovascular loop rules out radiofrequency ablation in favour of the open surgical procedure microvascular decompression is not supported by clinical evidence, and many patients with a neurovascular loop have been treated successfully with radiofrequency ablation alone.
How is correct electrode position confirmed during radiofrequency ablation for trigeminal neuralgia?▼
By stimulating the nerve first and checking that the patient feels it in their usual pain distribution, before proceeding with ablation.
In This Series: Advances in Chronic Pain Treatment: The Latest Trends
- 1.Advances in Chronic Pain Treatment
- 2.Trigeminal Neuralgia: Radiofrequency Ablation vs Surgery
- 3.Cervicogenic Headache: When Neck Problems Cause Migraines
- 4.Sphenopalatine Ganglion Block: Cluster Headache, Migraine and Burning Mouth Syndrome
- 5.Cervical Radiculopathy: Why Most Neck-Related Arm Pain Doesn't Need Surgery
- 6.T2-T3 Sympathectomy for Complex Regional Pain Syndrome
- 7.Shoulder Pain Without Surgery: Adhesive Capsulitis and the 3-in-1 Block
- 8.Sciatica and Failed Back Surgery: Transforaminal Epidural Adhesiolysis
- 9.Discogenic Back Pain: Biacuplasty and Finding the Painful Disc
- 10.Cancer Pain Management: Sympathetic Nerve Blocks for Pelvic and Upper GI Cancer
- 11.Coccydynia and Pelvic Pain: Ganglion Impar and Pudendal Nerve Blocks
- 12.Knee Pain and Spinal Cord Stimulation: Advanced Options When Surgery Isn't Right
- 13.Opioids in Chronic Pain: When They're Safe, When They're Not