Chairman, Manipal Institute of Cardiac Sciences & Chief of Clinical Services, Manipal Hospital, Dwarka, New Delhi
Series overview · 7 articles
Robotic Assisted Cardiac Surgery
January 26, 2025
Dr. Yugal Kishore Mishra is Chairman of the Manipal Institute of Cardiac Sciences at Manipal Hospital. He introduced robotic cardiac surgery to India in 2002, the first surgeon in Asia to do so, and has operated on more than 30,000 patients over his career. This guide is based on a live Jivo Masterclass where he explained to doctors across Africa how minimally invasive and robotic techniques have changed valve repair and replacement, coronary artery bypass surgery and aortic surgery, and what a patient or a referring doctor actually needs to know before choosing one of these approaches.
The series that follows works through the definition and evolution of minimally invasive cardiac surgery, how valve repair and replacement is done through a small port instead of a full sternotomy, how coronary artery bypass surgery is performed with robotic and endoscopic harvesting of the bypass grafts, who is and isn't a suitable candidate, what the surgery costs and how recovery compares with conventional surgery, and how the training and referral pathway works for doctors and patients outside India.
From a 20-Centimetre Incision to No Incision at All
For most of the history of cardiac surgery, every operation on the heart meant splitting the sternum down the middle: a full sternotomy, an incision of roughly 20 centimetres, to expose the heart, connect it to a heart-lung machine and operate under direct vision. Around 20 to 25 years ago, surgeons worldwide began asking whether a full sternotomy was really necessary for every case. The answer was no: a valve could be reached through an upper or lower partial sternotomy, or through a small thoracotomy between the ribs, without cutting the whole sternum at all. Dr. Mishra's own definition of minimally invasive cardiac surgery is simple: any operation performed without a full sternotomy, or without a heart-lung machine, qualifies. Manipal Hospital's programme started in 1997, and has since trained cardiac surgeons from France, Germany, the United States, Sri Lanka, Nepal, Bangladesh and Thailand, alongside 144 surgeons overall who have trained there and gone on to operate independently.
What Can Be Done Without Opening the Chest
The range of procedures covered by minimally invasive cardiac surgery is broader than most referring doctors expect: coronary artery bypass surgery, mitral and tricuspid valve repair and replacement, aortic valve repair and replacement, closure of atrial and ventricular septal defects, and removal of cardiac tumours such as myxomas. Three technical problems have to be solved for any of these procedures to work without a full sternotomy: access to the surgical site, visualisation of structures that can no longer be seen and touched directly, and achieving a still heart with adequate myocardial protection. Long, specially designed cannulas and instruments solve access; endoscopes, video assistance and now robotic systems solve visualisation; and cardioplegia delivered through a small, remotely placed aortic clamp solves the third.
Who Actually Qualifies
Age and vessel size set the practical limits. Children under six years old generally have femoral vessels too small to cannulate safely; Dr. Mishra's own smallest case was a seven-year-old, cannulated with a 14 French femoral catheter, and roughly 3.2 millimetres is the minimum femoral artery size he considers workable. On the other end, relative contraindications include peripheral vascular disease, an aortic aneurysm or a condition that predisposes to aortic dissection such as Marfan syndrome, significant obesity and pleural scarring. Every candidate goes through a CT scan, echocardiogram, Doppler study of the femoral vessels and a pulmonary function test before the approach is confirmed, because some procedures require single-lung ventilation during surgery.
The Trade-Off: Cost Against Recovery
Minimally invasive and robotic cardiac surgery cost more than conventional surgery, by Dr. Mishra's own estimate roughly one and a half times as much, because of the specialised instruments and, for robotic cases, the cost of the robotic system itself. What that premium buys is a markedly shorter recovery: patients return to work in around three weeks rather than the three months of restricted activity that follows a full sternotomy, with less pain, less blood loss and a shorter ICU stay.
Training and Access for Doctors Outside India
Dr. Mishra trains five to ten surgeons a month at Manipal Hospital, and doctors from outside India can visit for one to four weeks of hands-on training, be proctored on cases in their own country, or refer a patient directly for treatment priced to what the patient can afford. He also pointed to SSI Mantra, an India-made robotic surgical system built specifically for cardiac work, as a lower-cost alternative to imported robotic systems, now running on roughly 25 to 30 installations across India and exported to Indonesia and the Philippines.
Doctors looking to refer a patient for minimally invasive or robotic cardiac surgery, or to arrange training, can get in touch with the Jivo Healthcare team.
This guide is based on a live Jivo Masterclass: Dr. Yugal Kishore Mishra taught doctors across Africa on January 26, 2025.
Watch the full recording, or read the guide above.
FROM THE LIVE Q&A
Jivo Doctor Partner (name unclear from transcript)
Can a myocardial bridge be treated with minimally invasive cardiac surgery (MICS)?
Dr. Yugal Kishore Mishra
Yes, with the help of a robot we can unroof the myocardial bridge without opening the chest. It's possible, provided we can locate the exact site of the bridge, and this is absolutely the best way to go, because we are not going to open the chest. With the robot, we unbridge that segment of the LIMA and remove the bridging myocardium.
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Frequently Asked Questions
Can you perform tetralogy of Fallot repair with a minimally invasive approach?▼
I don't do congenital cases. In congenital cases I only do ASD closure, sinus venosus ASDs and second-time ASDs. I don't do tetralogy of Fallot, but there are surgeons who are doing tetralogy of Fallot repair with a minimal access approach. If you have a patient, you can reach out to us and we'll help you get to the correct doctor at Manipal Hospital. In Manipal Bangalore we have cardiac surgeons doing tetralogy of Fallot repair with a minimal access approach.
Are there recurrences after repair and replacement of the valve in a patient who has suffered from valvulopathy?▼
Yes, there is always a possibility of failed repair, so the patient may require re-repair or replacement. Cleveland Clinic data shows that even in degenerative disease there is significant failure of repair after 10 years, and in a rheumatic segment specifically the failure rate is quite a bit higher. When we replace the valve with a tissue valve, we know that after 10 to 15 years tissue valves are going to fail. We now have a percutaneous TAVI valve which can be implanted without surgery if the patient already has a tissue valve in the aortic or mitral position. For a mechanical valve, if there is a failure in the form of a paravalvular leak or thrombus formation, we either do thrombolysis or have to re-replace the mechanical valve.
How can one improve his or her robotic surgery skills?▼
You need hands-on training. I started robotic surgery in India in 2002, the first time in Asia, and since then I have done around 700 robotic surgeries. In India we train people who want to come; I get at least five to ten people a month who come across India and also from other countries to get trained for robotic surgery. Intuitive Surgical, which makes the da Vinci system, was earlier reluctant but has now started looking at training in cardiac surgery. The good news is that we also have an India-made robotic system, SSI Mantra, specially designed for cardiac surgery, which is comparatively cheaper than the Intuitive robot and also best suited for cardiac surgery, and they also train. Countries like Indonesia and the Philippines have now started buying that system too, and in India we have around 25 to 30 systems working.
What type of cardiac surgery is preferred for robotic assistance?▼
What I am doing here is coronary artery bypass surgery, and the job of the robot for coronary artery bypass surgery is to take down the two mammary arteries with the help of the robot and then do the bypass, and direct valve repair and replacement with the robot. We also do atrial septal defect closure and removal of myxomas. Some surgeons have now started doing valve replacement with the robot, but I am not doing that. I'm not comfortable with it.
Is there any age contraindication for minimally invasive cardiac surgery?▼
For young patients, since in minimally invasive surgery we usually cannulate the femoral artery and vein, patients less than six years old have very small femoral arteries, so we avoid the minimal access approach in very young children. After six years, I have done ASD closure in a 7-year-old, putting in a 14 French femoral cannula, so up to about 3.2mm femoral artery size is appropriate for cannulation; less than that is not good. For older patients, the contraindications I already mentioned apply, such as atheromatous changes in the femoral artery, which is not good for cannulation, or changes in the ascending aorta, such as calcification, which is again not a good aorta for this. That's why beforehand we do a Doppler study of the femoral artery and vein to see the size and any lesions, and a CT scan to see the ascending aorta and the tortuosity of the iliac vessels.
In This Series: Robotic Assisted Cardiac Surgery
- 1.Robotic Assisted Cardiac Surgery
- 2.What Minimally Invasive Cardiac Surgery Actually Means
- 3.Minimally Invasive and Robotic Valve Repair and Replacement
- 4.Robotic and Minimally Invasive Coronary Artery Bypass Surgery
- 5.Who Qualifies for Minimally Invasive Cardiac Surgery
- 6.Recovery, Cost and Outcomes After Minimally Invasive Cardiac Surgery
- 7.Training the Next Generation of Robotic Cardiac Surgeons