Pain Medicine & Palliative CareDr. Ashu Kumar JainChronic Pain Management

Chief, Pain Medicine & Palliative Care, Artemis Hospitals, Gurgaon, India

Part 4 of 12 in Advances in Chronic Pain Management

Cervical Radiculopathy: Epidural Injection and Why Cathlab Safety Matters

June 8, 2025

Cervical disc disease causing radiculopathy in the upper limb does not automatically require surgery. In Dr. Jain's practice, only a small minority of these patients, those with myelopathy or significant motor weakness, around 3% of cases, need an operation; the remaining 95 to 97% can be treated with a cervical epidural injection of dexamethasone and normal saline, without surgery.

He describes an international patient weighing 135 kilograms who received a routine cervical epidural injection performed in a catheterisation lab rather than a standard X-ray suite. Contrast dye appeared as an abnormal dark streak on the initial image; a digital subtraction angiography run on the table, only possible because the procedure was being done in a cathlab, revealed the dye tracking into an extensive web of epidural veins rather than only the epidural space. Dr. Jain states plainly that had the medication been injected without catching this on cathlab imaging, the patient could have died on the table. He treats this case as the reason his practice performs these injections with cathlab-level imaging rather than fluoroscopy alone: it increases the success rate and reduces the chance of an undetected complication.

This guide is based on a live Jivo Masterclass — Dr. Ashu Kumar Jain taught doctors across Africa on June 8, 2025.

FROM THE LIVE Q&A

DR

Dr. Epa, DRC

How do you distinguish between pain caused by dyspepsia and pain caused by angina pectoris?

AK

Dr. Ashu Kumar Jain

That sits outside pain medicine. It belongs to cardiology and gastroenterology. This practice does not treat visceral pain originating from the heart or lungs and stays restricted to musculoskeletal and neuropathic pain.

See all 18 questions from this masterclass →

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Frequently Asked Questions

Patients often present with pain that has both a surgical solution and a pain-management solution. How do doctors decide when a patient needs surgery versus pain management?

Under international Spine Society guidelines, when the primary problem is pain alone, the patient does not need surgery, regardless of the degree of compression shown on imaging, as long as it is below L2. Surgery is indicated for disability: foot drop, motor deficit, sensory deficit, or more than moderate to severe canal stenosis on MRI, where an intervention can only buy time rather than treat the underlying disease. At Artemis, pain medicine and spine surgery work as a team. If a patient referred for pain turns out to have a neurological deficit, they go straight to the spine surgeon; if pain is the only presenting symptom, pain medicine treats it. The line between the two is clear.

Bone marrow transplant cures sickle cell disease but is not offered to every patient, partly for financial reasons. How can sickle cell patients with chronic pain from avascular necrosis of the femoral head benefit?

If the femoral head itself is involved, radiofrequency ablation of the hip joint, targeting the genicular nerves supplying the joint, is a very rewarding procedure. But if the pain originates from the bone itself or has a visceral component, high-dose NSAIDs risk the kidneys and the better approach is opioid-based: morphine or tramadol with paracetamol and a neuropathic agent, alongside any specific interventional target that exists.

Can you share more about deep brain stimulation for select cases in pain management?

That is not something done from pain medicine. Deep brain stimulation is coming up fast as a field, but at Artemis it sits with the neurosurgery team, not pain medicine. That question is better asked at a neurosurgery masterclass.

How should pain from compression of the L4 and L5 vertebrae be managed, given the overlap between spine surgery and pain management?

First establish whether it is lateral or central canal stenosis, and check for any sensory or motor deficit on examination. Without a deficit and with lateral canal stenosis, transforaminal epidural adhesiolysis gives wonderful results. With moderate to severe central stenosis, a real sensory or motor deficit, and pain that does not respond to a block, the patient needs surgery.

You mentioned opioids as a line of treatment for chronic pain from avascular necrosis in sickle cell disease. Does not that class of drug carry a risk of habit-formation or addiction?

Used for chronic low back pain, knee pain or similar musculoskeletal pain, yes, opioids are habit-forming. Used for cancer pain, and for sickle cell pain, which is managed on the same principles as cancer pain, they are never habit-forming in this experience. Opioids sit near the top of the WHO analgesic ladder, are safe on organ function, and are potent enough that patients do not become dependent in this context. Countries that prescribe opioids freely for ordinary chronic non-cancer pain, as parts of the United States and Europe have, do see patients become dependent. For routine non-cancer chronic pain, that risk is real and opioids should be avoided long-term.

Does cervical radiculopathy from a disc always need surgery?

No. Only a small minority of these patients, those with myelopathy or significant motor weakness, around 3% of cases, need surgery. The remaining 95 to 97% can be treated with a cervical epidural injection alone.

Why perform a cervical epidural injection in a catheterisation lab rather than a standard X-ray suite?

Because live imaging in a cathlab can reveal a complication, such as contrast dye tracking into an unexpected web of epidural veins, before it becomes dangerous. In one case, this catch is described as having potentially prevented a fatality on the table.

What is injected during a cervical epidural for radiculopathy?

Dexamethasone combined with normal saline.

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