Chief, Pain Medicine & Palliative Care, Artemis Hospitals, Gurgaon, India
Part 11 of 12 in Advances in Chronic Pain Management
Spinal Cord Stimulation and Intrathecal Pumps for Pain That Doesn't Respond to Anything Else
June 8, 2025
Spinal cord stimulation is reserved for neuropathic pain, ischaemic pain, complex regional pain syndrome and phantom limb pain that has not responded to other treatment. Dr. Jain describes a brachial plexus injury patient given a trial lead first, with good pain relief, and a separate case, a young patient who had become dependent on painkillers because of his untreated pain, who found good pain relief once a permanent lead was placed.
Intrathecal pumps deliver medication, baclofen for spasticity, or morphine or a morphine combination for pain such as failed back surgery syndrome, directly into the spinal fluid. One patient, from an African country, received an intrathecal baclofen pump for severe spasticity following a spinal cord injury and settled on 75 micrograms of baclofen with the rigidity resolved. Another patient, who had a tumour at T6 removed surgically in Iraq and developed severe spasticity afterward, could not tolerate being touched before treatment; Dr. Jain shows her again 24 hours after implantation of a combined morphine and baclofen intrathecal pump, by which point she had no pain and no spasticity.
This guide is based on a live Jivo Masterclass — Dr. Ashu Kumar Jain taught doctors across Africa on June 8, 2025.
FROM THE LIVE Q&A
Moderator
Would marijuana-based therapy sit in the same class as opioids for safety?
Dr. Ashu Kumar Jain
Marijuana is a safer drug than a typical opioid, including for musculoskeletal as well as visceral pain, and some countries now use synthetic formulations of it. It just is not approved for medical use in India yet.
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Frequently Asked Questions
NSAIDs also carry a risk of kidney damage for musculoskeletal pain. What is the practical limit?▼
For a musculoskeletal complaint, an NSAID and a muscle relaxant should not run past seven to ten days, at most two weeks. With a new patient, the first move is not intervention: a two-week medical trial is given first, against a target of at least 50% pain relief. If that trial fails to deliver it, the next step is intervention, straight away.
Is there a list of drugs under your remit that are specialist-prescription only, and how do you manage the supply side, including the shelf life and storage of these medicines?▼
In India, opioids are scheduled drugs. Prescribing requires a competent doctor, meaning a pain specialist, anaesthesiologist or neurologist, not a general physician, general surgeon or ENT. For morphine and fentanyl specifically, the hospital needs a government licence to hold a set quantity, uses a special designated government form that gets stamped, and patients are required to bring back a consumption chart that is submitted to the drug controller. Tramadol, tapentadol and buprenorphine do not need that special licensing, but they still require a valid, stamped prescription from a competent doctor.
Given that supply and prescription control is so tight for opioids, is not it strange that some restricted painkiller combinations are still sold over the counter in India?▼
That gap exists, and it falls to drug inspectors to enforce, not to prescribing doctors. In practice it means a large number of chronic pain patients arrive in this clinic having self-medicated with over-the-counter combination painkillers for five, ten, even twenty years. This practice calls it analgesic abuse: a difficult situation created by the fact that these medicines are freely available without a prescription.
What are the most common misconceptions community doctors have about facet joint injection?▼
The first problem is diagnosis. Ninety per cent of doctors who are not trained for this kind of spinal pain cannot diagnose facetogenic pain. This practice groups facetogenic and discogenic pain together as axial pain, and gabapentinoids have no role in treating it, yet eight in ten axial pain patients are put on these drugs anyway, with zero results. Getting it right needs a specific history, a specific examination, and then a diagnostic block to confirm the pain is actually coming from the facet before moving to facet joint radiofrequency ablation.
How should pain from a sickle cell crisis be managed?▼
A crisis needs aggressive fluid management and correction of the patient's pH and blood gases. These patients do not respond to diclofenac or similar painkillers; they need intravenous opioids, usually through patient-controlled analgesia while admitted. Once the patient stabilises and comes out of crisis, treatment switches to patches or oral medication.
What conditions is spinal cord stimulation used for?▼
Neuropathic pain, ischaemic pain, complex regional pain syndrome and phantom limb pain, generally after other treatments have not worked, and usually preceded by a trial lead.
What is delivered through an intrathecal pump, and for what conditions?▼
Baclofen for spasticity, or morphine or a morphine combination for pain conditions such as failed back surgery syndrome, delivered directly into the spinal fluid rather than systemically.
How quickly can an intrathecal pump relieve severe spasticity?▼
In one case involving a combined morphine and baclofen pump for post-surgical spasticity, the patient was pain-free and free of spasticity within 24 hours of implantation.
In This Series: Advances in Chronic Pain Management
- 1.Advances in Chronic Pain Management
- 2.Facial Pain: Trigeminal Neuralgia, Glossopharyngeal Neuralgia and Sphenopalatine Ganglion Block
- 3.Cervicogenic Headache and Neck Pain: Cervical Facet Radiofrequency Ablation
- 4.Cervical Radiculopathy: Epidural Injection and Why Cathlab Safety Matters
- 5.Thoracic Facetogenic Pain and T2-T3 Sympathectomy for the Upper Limb
- 6.Shoulder Pain Without Surgery: Adhesive Capsulitis and the Three-in-One Block
- 7.Failed Back Surgery, Sciatica and SI Joint Pain: Transforaminal Adhesiolysis and Facet RFA
- 8.Discogenic Low Back Pain: Biacuplasty and Intradiscal Radiofrequency Ablation
- 9.Cancer, Pelvic and Perineal Pain: Visceral Nerve Blocks and Ganglion Impar
- 10.Knee Pain Without Surgery: Cooled Radiofrequency Ablation and Regenerative Options
- 11.Spinal Cord Stimulation and Intrathecal Pumps for Pain That Doesn't Respond to Anything Else
- 12.Opioids and Sickle Cell Pain: When They Are Habit-Forming and When They Are Not