Pain Medicine & Palliative CareDr. Ashu Kumar JainChronic Pain Management

Chief, Pain Medicine & Palliative Care, Artemis Hospitals, Gurgaon, India

Part 5 of 12 in Advances in Chronic Pain Management

Thoracic Facetogenic Pain and T2-T3 Sympathectomy for the Upper Limb

June 8, 2025

Thoracic facetogenic pain, felt travelling from the back of the chest to the front, keeps patients awake at night and is frequently left undiagnosed; a video Dr. Jain posted on this exact pattern of midback pain drew more than 3 million views, reflecting how many patients search for an explanation they are not getting from their own doctors. Radiofrequency ablation of the thoracic facets treats this pain directly and, in his account, gives consistently good results in patients who had been living with untreated midback pain for years.

T2-T3 sympathectomy addresses a different set of conditions: complex regional pain from brachial plexus injury, post-surgical pain such as after breast cancer surgery, post-amputation pain, and peripheral vascular disease. Dr. Jain's institution performs this percutaneously, placing two electrodes at the T2-T3 level under imaging, rather than by the open thoracoscopic surgery he says remains standard elsewhere. One case involved a patient with a vascular emergency and a visibly darkened, ischaemic hand who was not recovering after an earlier amputation; the team was called in overnight to perform sympathectomy. He describes it as one of the most rewarding procedures for brachial plexus injury pain, delivered on a day-care basis without open surgery.

This guide is based on a live Jivo Masterclass — Dr. Ashu Kumar Jain taught doctors across Africa on June 8, 2025.

FROM THE LIVE Q&A

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Moderator

Patients often present with pain that has both a surgical solution and a pain-management solution. How do doctors decide when a patient needs surgery versus pain management?

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Dr. Ashu Kumar Jain

Under international Spine Society guidelines, when the primary problem is pain alone, the patient does not need surgery, regardless of the degree of compression shown on imaging, as long as it is below L2. Surgery is indicated for disability: foot drop, motor deficit, sensory deficit, or more than moderate to severe canal stenosis on MRI, where an intervention can only buy time rather than treat the underlying disease. At Artemis, pain medicine and spine surgery work as a team. If a patient referred for pain turns out to have a neurological deficit, they go straight to the spine surgeon; if pain is the only presenting symptom, pain medicine treats it. The line between the two is clear.

See all 18 questions from this masterclass →

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Frequently Asked Questions

Bone marrow transplant cures sickle cell disease but is not offered to every patient, partly for financial reasons. How can sickle cell patients with chronic pain from avascular necrosis of the femoral head benefit?

If the femoral head itself is involved, radiofrequency ablation of the hip joint, targeting the genicular nerves supplying the joint, is a very rewarding procedure. But if the pain originates from the bone itself or has a visceral component, high-dose NSAIDs risk the kidneys and the better approach is opioid-based: morphine or tramadol with paracetamol and a neuropathic agent, alongside any specific interventional target that exists.

Can you share more about deep brain stimulation for select cases in pain management?

That is not something done from pain medicine. Deep brain stimulation is coming up fast as a field, but at Artemis it sits with the neurosurgery team, not pain medicine. That question is better asked at a neurosurgery masterclass.

How should pain from compression of the L4 and L5 vertebrae be managed, given the overlap between spine surgery and pain management?

First establish whether it is lateral or central canal stenosis, and check for any sensory or motor deficit on examination. Without a deficit and with lateral canal stenosis, transforaminal epidural adhesiolysis gives wonderful results. With moderate to severe central stenosis, a real sensory or motor deficit, and pain that does not respond to a block, the patient needs surgery.

You mentioned opioids as a line of treatment for chronic pain from avascular necrosis in sickle cell disease. Does not that class of drug carry a risk of habit-formation or addiction?

Used for chronic low back pain, knee pain or similar musculoskeletal pain, yes, opioids are habit-forming. Used for cancer pain, and for sickle cell pain, which is managed on the same principles as cancer pain, they are never habit-forming in this experience. Opioids sit near the top of the WHO analgesic ladder, are safe on organ function, and are potent enough that patients do not become dependent in this context. Countries that prescribe opioids freely for ordinary chronic non-cancer pain, as parts of the United States and Europe have, do see patients become dependent. For routine non-cancer chronic pain, that risk is real and opioids should be avoided long-term.

The physiology of the drug and the brain's receptors are the same either way, so why is not it habit-forming in sickle cell disease and cancer the way it is elsewhere?

Because sickle cell pain and cancer pain are primarily visceral pain, and viscera carry opioid receptors. Back pain, knee pain, elbow pain and shoulder pain are peripheral, musculoskeletal or neuropathic pain, and that tissue does not carry the same opioid receptor expression. Visceral pain is also carried by the body's sympathetic nervous system, which does not respond to conventional painkillers, so it needs a neuropathic agent and an opioid in combination. That is the physiological difference.

What is thoracic facetogenic pain and how common is it?

Pain that travels from the back to the front of the chest, disrupting sleep. It is frequently undiagnosed; a video on this exact symptom pattern drew more than 3 million views, reflecting how many patients go unexplained.

What conditions does T2-T3 sympathectomy treat?

Complex regional pain from brachial plexus injury, post-surgical pain such as after breast cancer surgery, post-amputation pain, and peripheral vascular disease that has not responded to conventional treatment.

Is T2-T3 sympathectomy done as open surgery?

Not in this practice. It is performed percutaneously, placing two electrodes at the T2-T3 level under imaging, rather than through open thoracoscopic surgery.

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