Chief, Pain Medicine & Palliative Care, Artemis Hospitals, Gurgaon, India
Part 7 of 12 in Advances in Chronic Pain Management
Failed Back Surgery, Sciatica and SI Joint Pain: Transforaminal Adhesiolysis and Facet RFA
June 8, 2025
Caudal epidural block treats coccydynia-adjacent presentations, spinal stenosis, spondylolisthesis and failed back surgery syndrome, with contrast dye producing the characteristic inverted Christmas tree spread on imaging. For sciatica specifically, Dr. Jain uses transforaminal epidural adhesiolysis: the epidural space is washed with 5 to 7ml of saline and hyaluronidase at the affected level, clearing inflammatory material, and only 2mg of dexamethasone is used per level, a deliberately minimal steroid dose that he says still delivers good results.
When patients continue to have pain after spinal fixation, called adjacent-level disease, the same transforaminal approach can release a nerve root that has become trapped in scar tissue below or above the level of fixation, or treat an adjacent facet joint with radiofrequency ablation. Sacroiliac joint pain, whether degenerative or appearing months to years after a fixation surgery, is treated with SI joint injection and radiofrequency ablation; Dr. Jain describes one patient whose SI joint began paining about a year after a fixation procedure, treated successfully with radiofrequency ablation of the joint.
This guide is based on a live Jivo Masterclass — Dr. Ashu Kumar Jain taught doctors across Africa on June 8, 2025.
FROM THE LIVE Q&A
Dr. Ivan, Uganda
Can you share more about deep brain stimulation for select cases in pain management?
Dr. Ashu Kumar Jain
That is not something done from pain medicine. Deep brain stimulation is coming up fast as a field, but at Artemis it sits with the neurosurgery team, not pain medicine. That question is better asked at a neurosurgery masterclass.
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Frequently Asked Questions
How should pain from compression of the L4 and L5 vertebrae be managed, given the overlap between spine surgery and pain management?▼
First establish whether it is lateral or central canal stenosis, and check for any sensory or motor deficit on examination. Without a deficit and with lateral canal stenosis, transforaminal epidural adhesiolysis gives wonderful results. With moderate to severe central stenosis, a real sensory or motor deficit, and pain that does not respond to a block, the patient needs surgery.
You mentioned opioids as a line of treatment for chronic pain from avascular necrosis in sickle cell disease. Does not that class of drug carry a risk of habit-formation or addiction?▼
Used for chronic low back pain, knee pain or similar musculoskeletal pain, yes, opioids are habit-forming. Used for cancer pain, and for sickle cell pain, which is managed on the same principles as cancer pain, they are never habit-forming in this experience. Opioids sit near the top of the WHO analgesic ladder, are safe on organ function, and are potent enough that patients do not become dependent in this context. Countries that prescribe opioids freely for ordinary chronic non-cancer pain, as parts of the United States and Europe have, do see patients become dependent. For routine non-cancer chronic pain, that risk is real and opioids should be avoided long-term.
The physiology of the drug and the brain's receptors are the same either way, so why is not it habit-forming in sickle cell disease and cancer the way it is elsewhere?▼
Because sickle cell pain and cancer pain are primarily visceral pain, and viscera carry opioid receptors. Back pain, knee pain, elbow pain and shoulder pain are peripheral, musculoskeletal or neuropathic pain, and that tissue does not carry the same opioid receptor expression. Visceral pain is also carried by the body's sympathetic nervous system, which does not respond to conventional painkillers, so it needs a neuropathic agent and an opioid in combination. That is the physiological difference.
Would marijuana-based therapy sit in the same class as opioids for safety?▼
Marijuana is a safer drug than a typical opioid, including for musculoskeletal as well as visceral pain, and some countries now use synthetic formulations of it. It just is not approved for medical use in India yet.
NSAIDs also carry a risk of kidney damage for musculoskeletal pain. What is the practical limit?▼
For a musculoskeletal complaint, an NSAID and a muscle relaxant should not run past seven to ten days, at most two weeks. With a new patient, the first move is not intervention: a two-week medical trial is given first, against a target of at least 50% pain relief. If that trial fails to deliver it, the next step is intervention, straight away.
How much steroid is used in transforaminal epidural adhesiolysis for sciatica?▼
Only 2mg of dexamethasone per level, a deliberately minimal dose, alongside 5 to 7ml of saline and hyaluronidase to wash the epidural space.
Can pain after spinal fixation surgery (failed back surgery) be treated without another operation?▼
Often, yes. A trapped nerve root in scar tissue can be released with a transforaminal approach, and pain from an adjacent facet joint or the SI joint can be treated with radiofrequency ablation, without repeat surgery.
What causes SI joint pain after spinal fixation?▼
It can appear months to years after fixation surgery as the SI joint itself becomes symptomatic. It is treated with SI joint injection and radiofrequency ablation.
In This Series: Advances in Chronic Pain Management
- 1.Advances in Chronic Pain Management
- 2.Facial Pain: Trigeminal Neuralgia, Glossopharyngeal Neuralgia and Sphenopalatine Ganglion Block
- 3.Cervicogenic Headache and Neck Pain: Cervical Facet Radiofrequency Ablation
- 4.Cervical Radiculopathy: Epidural Injection and Why Cathlab Safety Matters
- 5.Thoracic Facetogenic Pain and T2-T3 Sympathectomy for the Upper Limb
- 6.Shoulder Pain Without Surgery: Adhesive Capsulitis and the Three-in-One Block
- 7.Failed Back Surgery, Sciatica and SI Joint Pain: Transforaminal Adhesiolysis and Facet RFA
- 8.Discogenic Low Back Pain: Biacuplasty and Intradiscal Radiofrequency Ablation
- 9.Cancer, Pelvic and Perineal Pain: Visceral Nerve Blocks and Ganglion Impar
- 10.Knee Pain Without Surgery: Cooled Radiofrequency Ablation and Regenerative Options
- 11.Spinal Cord Stimulation and Intrathecal Pumps for Pain That Doesn't Respond to Anything Else
- 12.Opioids and Sickle Cell Pain: When They Are Habit-Forming and When They Are Not