Preventing Coronary Artery Disease: Lifestyle, Risk Stratification and Regular Screening

One ECG showing borderline bradycardia, combined with a two-year history that has defeated standard testing, points toward right coronary artery disease, which is notoriously difficult to pick up outside direct angiography. Pending access to a coronary angiogram, start dual antiplatelet therapy, 75 mg of clopidogrel and 150 mg of aspirin daily, plus a statin at 40 mg daily to stabilize the plaque, and check cardiac enzymes at his next chest pain episode. A positive enzyme without an ECG change would classify him as unstable angina, since that diagnosis only requires a troponin derangement alongside chest pain, not an ECG change. A strong maternal family history of cardiac illness is relevant here even though he is young and does not smoke or drink.

RFCL is an old scoring system we do not use anymore; it produces more false negatives than anything useful. Score this patient with a EuroSCORE now, and a SYNTAX score once an angiogram is available.

Before 45, women have high estrogen and regular cycles, giving them roughly one-eighth the coronary risk of a man. After menopause, that risk is still about half of a man's, but it rises four-fold from her own prior baseline. The presentation also changes: expect a longer course, days rather than hours, with softer symptoms, a flu-like feeling or mild chest tightness, that get mistaken for a common cold. The best test in this group is a CT coronary angiogram, because women tend to have a lower coronary calcium load, which gives CT angiography a strong positive predictive value for them specifically. Diabetics have a parallel but distinct problem: autonomic nerve involvement blunts the pain signal, so they report less chest pain for the same severity of disease while still showing the nausea, fatigue and cold extremities of an infarction. Physicians need to actively look for the disease in diabetics rather than wait for classic pain.

The same as anyone else. He gets a coronary angiogram under a universal precautions pathway, and if he has coronary artery disease, it is stentable or operable exactly as it would be otherwise. Any JCI-accredited hospital, ours included, has a protocol to isolate and properly treat these patients. People living with HIV are not discriminated against in access to stenting or bypass surgery.

The two are differentiated by troponin: a pectoralis muscle spasm will always return a negative troponin test. There is not really a single first-choice management for a direct link between the two, because they do not co-occur as one diagnosis; one patient might have non-cardiac chest pain from a muscle spasm and separately have coronary disease. Treat each on its own terms: non-steroidal anti-inflammatory drugs for the muscle spasm, and the angiography pathway, deciding between angioplasty and bypass, if there is genuine coronary disease.

More than two hours a week, roughly the equivalent of half an hour a day on weekdays, combined with the rest of the prevention checklist.

No. The American Heart Association's position, cited as settling a long-running controversy, is that no amount of alcohol confers a protective benefit for the heart.

Every three months, as part of routine tracking for every chronic disease patient.

Order regular blood work, maintain a record for every patient, and use those numbers to stratify each patient into high, moderate or low cardiovascular risk, so surveillance can be adjusted before a cardiac event occurs.